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XB-PHENO-24028

Xla Wt + nsd2 MO, Mills A et al. (2019)

Experiment + Assay: Xla Wt + nsd2 MO + NF40 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection nsd2 MO1 nsd2.L
 NF stage 3 (4-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 40 to NF stage 40  
Anatomical Phenotypes: abnormal craniofacial region morphology , increased size of the head
Human Disease Associations: Wolf-Hirschhorn syndrome
Source: Fig. 3B, FGHI
Article: XB-ART-55919, PubMed