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XB-PHENO-24166

Xtr Wt + copb1 CRISPR, Macken WL et al. (2021)

Experiment + Assay: Xtr Wt + copb1 CRISPR + NF41 (3D imaging)
Background: Xtr.Nigerian1EXRC
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR  
NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
3D imaging NF stage 41  
Anatomical Phenotypes: abnormal brain morphology, abnormal eye morphology, abnormal forebrain morphology, abnormal head morphology, abnormal lens, decreased size of the chondrocranium, decreased size of the eye, decreased size of the forebrain, decreased size of the hindbrain, decreased size of the midbrain, decreased width of the head
Human Disease Associations: cataract, microcephaly
Source: Fig. 5 FIL
Article: XB-ART-57855, PubMed