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XB-PHENO-24254

Xtr Wt + fgfr4 CRISPR, Sempou E et al. (2018)

Experiment + Assay: Xtr Wt + fgfr4 CRISPR + NF19 (in situ hybridization)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR fgfr4 fgfr4
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 19 to NF stage 19  
Expression Phenotypes (1):
decreased amount dand5 expression in left-right organizer
Human Disease Associations: congenital heart disease, visceral heterotaxy
Source: Fig. 2 B
Article: XB-ART-55550, PubMed