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XB-PHENO-24270

Xtr Wt + fgfr4 CRISPR, Sempou E et al. (2018)

Experiment + Assay: Xtr Wt + fgfr4 CRISPR + NF12 (in situ hybridization)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR fgfr4 fgfr4
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 12 to NF stage 12  
Expression Phenotypes (1):
decreased amount tbxt expression in presumptive paraxial mesoderm
Human Disease Associations: congenital heart disease, visceral heterotaxy
Source: Fig. 5 L
Article: XB-ART-55550, PubMed