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XB-PHENO-24310

Xla Wt + sqstm1 MO + vangl2 MO, Puvirajesinghe TM et al. (2016)

Experiment + Assay: Xla Wt + sqstm1 MO + vangl2 MO + NF22-44 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection vangl2 MO2 vangl2 (Xla)
 NF stage 2 (2-cell) blastomere
morpholino injection sqstm1 MO1 sqstm1 (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 22 to NF stage 44  
Anatomical Phenotypes: abnormal convergent extension involved in axis elongation , abnormal neural tube closure , decreased length of anterior-posterior axis
Source: Fig. 6 c
Article: XB-ART-52202, PubMed