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XB-PHENO-24474

Xla Wt + six1 MO + mcrs1 MO, Neilson KM et al. (2020)

Experiment + Assay: Xla Wt + six1 MO + mcrs1 MO + NF13-18 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection mcrs1 MO1 mcrs1 (Xla)
 NF stage 4 (8-cell) animal blastomere
morpholino injection six1 MO1 six1 (Xla)
 NF stage 4 (8-cell) animal blastomere
morpholino injection mcrs1 MO2 mcrs1 (Xla)
 NF stage 4 (8-cell) animal blastomere
morpholino injection six1 MO2 six1 (Xla)
 NF stage 4 (8-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 13 to NF stage 18  
Expression Phenotypes (2):
increased amount irx1.L expression in preplacodal ectoderm
decreased amount irx1.L expression in preplacodal ectoderm
Source: Fig. 5 G col 2
Article: XB-ART-57914, PubMed