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XB-PHENO-24592

Xla Wt + six1-VP16, Mehdizadeh T et al. (2021)

Experiment + Assay: Xla Wt + six1-VP16 + NF26-32 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection six1 six1
 NF stage 4 (8-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 26 to NF stage 32  
Anatomical Phenotypes: increased size of the otic vesicle
Expression Phenotypes (1):
increased amount prdm1.L expression in otic vesicle
Human Disease Associations: branchiootorenal syndrome
Source: Fig. 2FG
Article: XB-ART-58245, PubMed