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XB-PHENO-24634

Xla Wt + hmgn1 MO, Ihewulezi C and Saint-Jeannet JP (2021)

Experiment + Assay: Xla Wt + hmgn1 MO + NF45 (stained tissue microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection hmgn1 MO1 hmgn1 (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
stained tissue microscopy NF stage 45  
Anatomical Phenotypes: abnormal ceratohyal morphology , abnormal chondrocranium morphology , abnormal gill primordium morphology , abnormal Meckel's cartilage morphology , decreased size of the chondrocranium
Human Disease Associations: microcephaly
Source: Figure 7 b, c
Article: XB-ART-58423, PubMed