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XB-PHENO-24722

Xla Wt + dvl3 MO + dvl1 MO, Lienkamp S et al. (2010)

Experiment + Assay: Xla Wt + dvl3 MO + dvl1 MO + NF33/34-40 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection dvl1 MO1 dvl1 (Xla)
 NF stage 3 (4-cell) animal hemisphere
morpholino injection dvl3 MO1 dvl3 (Xla)
 NF stage 3 (4-cell) animal hemisphere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 33 and 34 to NF stage 40  
Anatomical Phenotypes: abnormal development of pronephric kidney , abnormal pronephric kidney morphology
Human Disease Associations: nephronophthisis 2
Source: Fig. S 6 D
Article: XB-ART-42213, PubMed