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XB-PHENO-24744

Xtr Wt + ift172 CRISPR, Getwan M et al. (2021)

Experiment + Assay: Xtr Wt + ift172 CRISPR + NF62-63 (Other Detection Assay)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR ift172 gRNA1 ift172
 NF stage 2 (2-cell) left blastomere
Conditions:
Assay Type Assay Stages Antibody
Other Detection Assay NF stage 62 to NF stage 63  
Anatomical Phenotypes: abnormal forelimb digit morphology , abnormal hindlimb digit morphology , abnormally increased number of digit , decreased length of forelimb , decreased length of hindlimb , decreased length of hindlimb digit , decreased size of the forelimb digit
Human Disease Associations: kidney disease, ciliopathy, polydactyly
Source: Fig. 1 C bottom, Sup. Fig. 1 g
Article: XB-ART-58465, PubMed