Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-24751

Xtr Wt + ift172 CRISPR, Getwan M et al. (2021)

Experiment + Assay: Xtr Wt + ift172 CRISPR + NF37/38-42 (immunohistochemistry)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR ift172 gRNA1 ift172
 NF stage 2 (2-cell) left blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 37 and 38 to NF stage 42 Tuba4b Ab4
Anatomical Phenotypes: abnormally decreased number of cilium in the multiciliated cell, decreased size of the cilium in the multiciliated cell
Human Disease Associations: kidney disease, ciliopathy, polydactyly
Source: Fig. 2 K bottom L
Article: XB-ART-58465, PubMed