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XB-PHENO-24762

Xtr Wt + ift172 CRISPR, Getwan M et al. (2021)

Experiment + Assay: Xtr Wt + ift172 CRISPR + NF35/36 (immunohistochemistry)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR ift172 gRNA1 ift172
 NF stage 2 (2-cell) left blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 35 and 36 to NF stage 35 and 36  
Anatomical Phenotypes: abnormal cilium morphology in the multiciliated epidermal cell
Human Disease Associations: kidney disease, ciliopathy
Source: Fig. 6 C D row 4, Sup. Fig. 7
Article: XB-ART-58465, PubMed