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XB-PHENO-24792

Xla Wt + bicc1 MO + dand5 MO, Maerker M et al. (2021)

Experiment + Assay: Xla Wt + bicc1 MO + dand5 MO + NF20 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection bicc1 MO3 bicc1 (Xla)
 NF stage 3 (4-cell) right blastomere
morpholino injection dand5 MO3 dand5 (Xla)
 NF stage 3 (4-cell) right blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 20 to NF stage 20  
Anatomical Phenotypes: abnormal determination of left/right symmetry
Expression Phenotypes (1):
decreased amount dand5.L expression in left-right organizer
Source: Fig. 5 B C
Article: XB-ART-58455, PubMed