Phenotype: XB-PHENO-25136

XB-PHENO-25136

Wt + pou5f3.2 MO + pou5f3.3 MO + sox3 MO, Gentsch GE et al. (2019)

Experiment + Assay:

Wt + pou5f3.2 MO + pou5f3.3 MO + sox3 MO + NF9 (RNA-Seq)

Background:

Xtr.Outbred

Manipulations:

Manipulation Type	Reagent	Target Gene	Stage	Treatment Area
morpholino injection	pou5f3.2 MO7	pou5f3.2	NF stage 1	zygote
morpholino injection	pou5f3.3 MO6	pou5f3.3	NF stage 1	zygote
morpholino injection	sox3 MO5	sox3	NF stage 1	zygote

Conditions:

Assay Type	Assay Stages	Antibody
RNA-Seq	NF stage 9

Expression Phenotypes (464):

decreased amount abo.3 expression in the embryo

decreased amount acer1 expression in the embryo

decreased amount admp2 expression in the embryo

decreased amount ag1 expression in the embryo

decreased amount akain1 expression in the embryo

decreased amount akap12 expression in the embryo

decreased amount alcam expression in the embryo

decreased amount aldh1l1 expression in the embryo

decreased amount amotl2 expression in the embryo

decreased amount angpt4.2 expression in the embryo

decreased amount angpt4 expression in the embryo

decreased amount ano9 expression in the embryo

decreased amount anxa1.3 expression in the embryo

decreased amount apbb3 expression in the embryo

increased amount apbb3 expression in the embryo

decreased amount apela expression in the embryo

increased amount aqp1 expression in the embryo

decreased amount arhgap27 expression in the embryo

decreased amount arhgef38 expression in the embryo

decreased amount arhgef40 expression in the embryo

decreased amount arl4c expression in the embryo

decreased amount astl2c expression in the embryo

decreased amount astl2d.1 expression in the embryo

decreased amount atg16l1 expression in the embryo

decreased amount atp12a-like expression in the embryo

increased amount atp6v0a4 expression in the embryo

decreased amount atp6v0d2 expression in the embryo

decreased amount avd expression in the embryo

decreased amount b4galt1l expression in the embryo

decreased amount birc2 expression in the embryo

decreased amount bmp4 expression in the embryo

increased amount btg5.1 expression in the embryo

decreased amount c10h20orf96 expression in the embryo

increased amount c1orf162l expression in the embryo

decreased amount c5h1orf115 expression in the embryo

decreased amount c7 expression in the embryo

decreased amount c7orf31 expression in the embryo

increased amount capns1 expression in the embryo

decreased amount capns1 expression in the embryo

increased amount cat1 expression in the embryo

increased amount cav1 expression in the embryo

increased amount ccn1l expression in the embryo

increased amount ccnb5 expression in the embryo

decreased amount cdc25b expression in the embryo

decreased amount cdx1 expression in the embryo

decreased amount cdx2 expression in the embryo

decreased amount cdx4 expression in the embryo

decreased amount cenpv expression in the embryo

increased amount cfp expression in the embryo

increased amount chdh expression in the embryo

increased amount chrna10 expression in the embryo

increased amount chst6 expression in the embryo

decreased amount cnfn.1 expression in the embryo

increased amount cnn1 expression in the embryo

decreased amount cnn2 expression in the embryo

decreased amount cnrip1 expression in the embryo

increased amount cpa6 expression in the embryo

increased amount cpeb1 expression in the embryo

decreased amount cpe expression in the embryo

decreased amount crabp2 expression in the embryo

decreased amount cxcl12 expression in the embryo

decreased amount cyb561 expression in the embryo

decreased amount cyp26a1 expression in the embryo

decreased amount cyp2a6.1 expression in the embryo

decreased amount darmin expression in the embryo

decreased amount dennd2c expression in the embryo

decreased amount dgka expression in the embryo

decreased amount dhh expression in the embryo

decreased amount dixdc1 expression in the embryo

increased amount dlg4 expression in the embryo

decreased amount dll1 expression in the embryo

decreased amount dusp1 expression in the embryo

decreased amount dyrk2 expression in the embryo

decreased amount eef1a1o expression in the embryo

decreased amount elapor2 expression in the embryo

decreased amount elavl3 expression in the embryo

decreased amount elovl3 expression in the embryo

increased amount eml3 expression in the embryo

increased amount en1 expression in the embryo

decreased amount epas1 expression in the embryo

decreased amount eps8l1 expression in the embryo

increased amount etv2 expression in the embryo

decreased amount etv2 expression in the embryo

decreased amount f3 expression in the embryo

decreased amount fam110c expression in the embryo

increased amount fam20a.2 expression in the embryo

increased amount fev expression in the embryo

increased amount fezf2 expression in the embryo

decreased amount fezf2 expression in the embryo

decreased amount fgd1 expression in the embryo

decreased amount fgf20 expression in the embryo

decreased amount fmo3 expression in the embryo

increased amount fmo3 expression in the embryo

increased amount fmod expression in the embryo

decreased amount fndc10 expression in the embryo

decreased amount foxa1 expression in the embryo

decreased amount foxb1 expression in the embryo

decreased amount foxd3 expression in the embryo

decreased amount foxd4l1.1 expression in the embryo

decreased amount foxd4l1.2 expression in the embryo

decreased amount foxi1 expression in the embryo

decreased amount foxi4.2 expression in the embryo

decreased amount fth1.1 expression in the embryo

decreased amount fucolectin expression in the embryo

increased amount fucolectin expression in the embryo

decreased amount fzd10 expression in the embryo

decreased amount fzd4 expression in the embryo

decreased amount g2e3 expression in the embryo

decreased amount gas2l1 expression in the embryo

decreased amount gatm expression in the embryo

decreased amount gdap2 expression in the embryo

decreased amount gdf2 expression in the embryo

increased amount gdpd3 expression in the embryo

decreased amount gfod1 expression in the embryo

decreased amount gli1 expression in the embryo

decreased amount gmnc expression in the embryo

decreased amount gng13 expression in the embryo

increased amount gnrhr expression in the embryo

decreased amount gpr82 expression in the embryo

decreased amount gpx2 expression in the embryo

increased amount gsx2 expression in the embryo

increased amount gypc expression in the embryo

decreased amount h2ac12 expression in the embryo

increased amount h2ac12 expression in the embryo

decreased amount hal.1 expression in the embryo

decreased amount hap1 expression in the embryo

decreased amount has1 expression in the embryo

decreased amount herpud1 expression in the embryo

decreased amount hes3 expression in the embryo

decreased amount hes5.10 expression in the embryo

decreased amount hes5.1 expression in the embryo

decreased amount hes5.7 expression in the embryo

decreased amount hesx1 expression in the embryo

decreased amount hgf expression in the embryo

decreased amount homeobox100496651-provisional expression in the embryo

decreased amount hoxa1 expression in the embryo

decreased amount hoxd1 expression in the embryo

increased amount hoxd9 expression in the embryo

decreased amount hpdl expression in the embryo

decreased amount hsd17b12 expression in the embryo

increased amount hsd3b1 expression in the embryo

increased amount hspb7 expression in the embryo

increased amount htr5a expression in the embryo

decreased amount hunk expression in the embryo

increased amount icoslg expression in the embryo

increased amount id4 expression in the embryo

increased amount ifitm10 expression in the embryo

decreased amount ift43 expression in the embryo

decreased amount igf3 expression in the embryo

increased amount il10rb expression in the embryo

increased amount il18bp expression in the embryo

decreased amount inka1 expression in the embryo

increased amount irak2 expression in the embryo

decreased amount irx2 expression in the embryo

decreased amount itpka expression in the embryo

increased amount itpkb expression in the embryo

increased amount kcnf1 expression in the embryo

increased amount kcnj11 expression in the embryo

increased amount kcnj21 expression in the embryo

decreased amount kcnk6 expression in the embryo

decreased amount kctd15 expression in the embryo

decreased amount kitlg expression in the embryo

decreased amount klf17 expression in the embryo

decreased amount krt70 expression in the embryo

decreased amount krt7 expression in the embryo

decreased amount lef1 expression in the embryo

decreased amount lhx5 expression in the embryo

increased amount LOC100485356 expression in the embryo

increased amount LOC100485739 expression in the embryo

decreased amount LOC100485898 expression in the embryo

decreased amount LOC100485974 expression in the embryo

increased amount LOC100486155 expression in the embryo

decreased amount LOC100487159 expression in the embryo

decreased amount LOC100487186 expression in the embryo

increased amount LOC100487273 expression in the embryo

decreased amount LOC100487499 expression in the embryo

decreased amount LOC100487973 expression in the embryo

decreased amount LOC100488176 expression in the embryo

decreased amount LOC100488209 expression in the embryo

decreased amount LOC100488554 expression in the embryo

increased amount LOC100488580 expression in the embryo

increased amount LOC100488747 expression in the embryo

increased amount LOC100489697 expression in the embryo

decreased amount LOC100489839 expression in the embryo

decreased amount LOC100490141 expression in the embryo

increased amount LOC100490565 expression in the embryo

increased amount LOC100490809 expression in the embryo

decreased amount LOC100490855 expression in the embryo

decreased amount LOC100490971 expression in the embryo

increased amount LOC100491399 expression in the embryo

increased amount LOC100491521 expression in the embryo

increased amount LOC100491571 expression in the embryo

increased amount LOC100491742 expression in the embryo

increased amount LOC100492142 expression in the embryo

increased amount LOC100493192 expression in the embryo

decreased amount LOC100493456 expression in the embryo

increased amount LOC100493584 expression in the embryo

increased amount LOC100493962 expression in the embryo

increased amount LOC100493985 expression in the embryo

decreased amount LOC100494255 expression in the embryo

decreased amount LOC100495124 expression in the embryo

decreased amount LOC100495222 expression in the embryo

increased amount LOC100495391 expression in the embryo

increased amount LOC100495886 expression in the embryo

increased amount LOC100495931 expression in the embryo

decreased amount LOC100496394 expression in the embryo

increased amount LOC100496875 expression in the embryo

decreased amount LOC100497175 expression in the embryo

increased amount LOC100497193 expression in the embryo

decreased amount LOC100498064 expression in the embryo

decreased amount LOC100498497 expression in the embryo

decreased amount LOC100498593 expression in the embryo

increased amount LOC101730532 expression in the embryo

increased amount LOC101731222 expression in the embryo

decreased amount LOC101731247 expression in the embryo

decreased amount LOC101731619 expression in the embryo

decreased amount LOC101731882 expression in the embryo

decreased amount LOC101731904 expression in the embryo

increased amount LOC101731963 expression in the embryo

increased amount LOC101732019 expression in the embryo

increased amount LOC101732464 expression in the embryo

decreased amount LOC101732476 expression in the embryo

increased amount LOC101732854 expression in the embryo

increased amount LOC101733000 expression in the embryo

increased amount LOC101733098 expression in the embryo

increased amount LOC101733271 expression in the embryo

increased amount LOC101734042 expression in the embryo

decreased amount LOC101734072 expression in the embryo

increased amount LOC101734461 expression in the embryo

increased amount LOC101734517 expression in the embryo

increased amount LOC101734526 expression in the embryo

increased amount LOC101734831 expression in the embryo

decreased amount LOC101734868 expression in the embryo

increased amount LOC101735070 expression in the embryo

increased amount LOC105946367 expression in the embryo

decreased amount LOC105947222 expression in the embryo

increased amount LOC105947475 expression in the embryo

increased amount LOC105948244 expression in the embryo

increased amount LOC108644502 expression in the embryo

increased amount LOC108645634 expression in the embryo

decreased amount LOC108645662 expression in the embryo

increased amount LOC108646252 expression in the embryo

increased amount LOC108647426 expression in the embryo

decreased amount LOC116406439 expression in the embryo

decreased amount LOC116406441 expression in the embryo

decreased amount LOC116406448 expression in the embryo

increased amount LOC116406529 expression in the embryo

decreased amount LOC116406628 expression in the embryo

increased amount LOC116406652 expression in the embryo

increased amount LOC116406863 expression in the embryo

increased amount LOC116406886 expression in the embryo

decreased amount LOC116407528 expression in the embryo

increased amount LOC116407569 expression in the embryo

increased amount LOC116407615 expression in the embryo

increased amount LOC116407696 expression in the embryo

decreased amount LOC116407772 expression in the embryo

increased amount LOC116407816 expression in the embryo

decreased amount LOC116407911 expression in the embryo

decreased amount LOC116407912 expression in the embryo

increased amount LOC116407982 expression in the embryo

increased amount LOC116408044 expression in the embryo

increased amount LOC116408230 expression in the embryo

increased amount LOC116408234 expression in the embryo

increased amount LOC116408236 expression in the embryo

increased amount LOC116408243 expression in the embryo

increased amount LOC116408345 expression in the embryo

increased amount LOC116408358 expression in the embryo

increased amount LOC116408764 expression in the embryo

decreased amount LOC116408818 expression in the embryo

increased amount LOC116408934 expression in the embryo

increased amount LOC116409443 expression in the embryo

increased amount LOC116409848 expression in the embryo

decreased amount LOC116410319 expression in the embryo

increased amount LOC116410826 expression in the embryo

increased amount LOC116410834 expression in the embryo

increased amount LOC116410870 expression in the embryo

increased amount LOC116410979 expression in the embryo

increased amount LOC116411112 expression in the embryo

decreased amount LOC116411115 expression in the embryo

decreased amount LOC116411472 expression in the embryo

increased amount LOC116411524 expression in the embryo

increased amount LOC116411595 expression in the embryo

decreased amount LOC116411650 expression in the embryo

increased amount LOC116412021 expression in the embryo

increased amount LOC116412207 expression in the embryo

increased amount LOC116412277 expression in the embryo

increased amount LOC116412608 expression in the embryo

increased amount LOC394967 expression in the embryo

increased amount LOC448276 expression in the embryo

decreased amount LOC595077 expression in the embryo

increased amount lonrf3 expression in the embryo

decreased amount lpar6 expression in the embryo

decreased amount lrrc8c expression in the embryo

decreased amount lsp1 expression in the embryo

increased amount mapk8ip1 expression in the embryo

increased amount marco expression in the embryo

decreased amount meis3 expression in the embryo

decreased amount mespb expression in the embryo

decreased amount mex3b expression in the embryo

increased amount MGC107780 expression in the embryo

decreased amount mid1ip1 expression in the embryo

decreased amount mmp14 expression in the embryo

decreased amount mn1 expression in the embryo

increased amount mrc2 expression in the embryo

decreased amount msln expression in the embryo

increased amount muc1 expression in the embryo

decreased amount myf5 expression in the embryo

decreased amount myo5c expression in the embryo

increased amount myod1 expression in the embryo

decreased amount myod1 expression in the embryo

increased amount nat8.4 expression in the embryo

increased amount nectin4 expression in the embryo

decreased amount nectin4 expression in the embryo

decreased amount nedd9 expression in the embryo

increased amount nefm expression in the embryo

decreased amount neurog3 expression in the embryo

decreased amount nova2 expression in the embryo

increased amount nr2e1 expression in the embryo

increased amount ntrk2 expression in the embryo

decreased amount ntrk2 expression in the embryo

increased amount nupr1 expression in the embryo

decreased amount ocm4.6 expression in the embryo

decreased amount olfm4 expression in the embryo

decreased amount olig3 expression in the embryo

decreased amount olig4 expression in the embryo

increased amount or52ak1c expression in the embryo

increased amount or5dn1 expression in the embryo

decreased amount p2ry11 expression in the embryo

decreased amount p2ry2 expression in the embryo

decreased amount pabir2 expression in the embryo

increased amount paqr8 expression in the embryo

increased amount pax8 expression in the embryo

decreased amount pgls expression in the embryo

increased amount pik3r6 expression in the embryo

decreased amount plekhn1 expression in the embryo

decreased amount plpp3 expression in the embryo

decreased amount pm20d1 expression in the embryo

increased amount pmp22 expression in the embryo

decreased amount pnhd expression in the embryo

decreased amount post2 expression in the embryo

decreased amount pou2f3 expression in the embryo

decreased amount ppl expression in the embryo

decreased amount prdm14 expression in the embryo

decreased amount ptch2 expression in the embryo

decreased amount ptger4 expression in the embryo

decreased amount ptgs2 expression in the embryo

decreased amount pydc1 expression in the embryo

decreased amount pygm expression in the embryo

increased amount pyurf expression in the embryo

increased amount rab25 expression in the embryo

decreased amount rab25 expression in the embryo

decreased amount rarg expression in the embryo

decreased amount rasgef1b expression in the embryo

decreased amount rasl11b expression in the embryo

decreased amount rbm47 expression in the embryo

increased amount rem1 expression in the embryo

decreased amount rgcc expression in the embryo

decreased amount rgs16 expression in the embryo

decreased amount rhob expression in the embryo

decreased amount rhov expression in the embryo

decreased amount ribc1 expression in the embryo

increased amount ripply3 expression in the embryo

increased amount rnf183 expression in the embryo

decreased amount ror2 expression in the embryo

decreased amount rpe65 expression in the embryo

decreased amount rspo2 expression in the embryo

decreased amount rspo3 expression in the embryo

decreased amount s1pr3 expression in the embryo

decreased amount s1pr5 expression in the embryo

decreased amount sall1 expression in the embryo

decreased amount sall3 expression in the embryo

increased amount samd10 expression in the embryo

decreased amount sbk1l expression in the embryo

decreased amount sds expression in the embryo

decreased amount selenop2l expression in the embryo

decreased amount sema3f expression in the embryo

increased amount septinl expression in the embryo

decreased amount serpina1 expression in the embryo

increased amount serpinh1 expression in the embryo

decreased amount sfrp2 expression in the embryo

decreased amount sh2d3c expression in the embryo

increased amount six2 expression in the embryo

decreased amount ska3 expression in the embryo

decreased amount skida1 expression in the embryo

increased amount sla2 expression in the embryo

increased amount slc15a2 expression in the embryo

decreased amount slc16a12 expression in the embryo

decreased amount slc16a9 expression in the embryo

decreased amount slc25a24 expression in the embryo

decreased amount slc27a2 expression in the embryo

decreased amount slc28a3 expression in the embryo

decreased amount slc2a11.3 expression in the embryo

increased amount slc30a8 expression in the embryo

increased amount slc32a1 expression in the embryo

increased amount slc39a4 expression in the embryo

decreased amount slc43a2 expression in the embryo

decreased amount slitrk1 expression in the embryo

decreased amount socs3l expression in the embryo

decreased amount sox21 expression in the embryo

decreased amount sox2 expression in the embryo

decreased amount stx19 expression in the embryo

decreased amount szl expression in the embryo

increased amount szl expression in the embryo

decreased amount tagln2 expression in the embryo

decreased amount tat expression in the embryo

increased amount tbx20 expression in the embryo

decreased amount tbxt.2 expression in the embryo

decreased amount tbxt expression in the embryo

decreased amount tdgf1.2 expression in the embryo

decreased amount tdgf1.3 expression in the embryo

increased amount tenm4 expression in the embryo

decreased amount tfap2a expression in the embryo

increased amount tfrcl expression in the embryo

decreased amount tmem150b expression in the embryo

increased amount tmem213 expression in the embryo

decreased amount tmem45a expression in the embryo

decreased amount tmem72 expression in the embryo

decreased amount tmprss9 expression in the embryo

increased amount tnfrsf12a expression in the embryo

decreased amount tnfrsf21 expression in the embryo

decreased amount tp63 expression in the embryo

decreased amount trex2 expression in the embryo

decreased amount trim29 expression in the embryo

increased amount trim32l expression in the embryo

decreased amount trpm4 expression in the embryo

increased amount ttpa expression in the embryo

increased amount twist1 expression in the embryo

increased amount uchl1 expression in the embryo

decreased amount ugt3a2 expression in the embryo

decreased amount unc45b expression in the embryo

decreased amount unc79 expression in the embryo

decreased amount upk2 expression in the embryo

decreased amount upk3b expression in the embryo

decreased amount usp43 expression in the embryo

increased amount vwa5a expression in the embryo

decreased amount vwa5a expression in the embryo

increased amount wnt7b expression in the embryo

increased amount wnt9b expression in the embryo

decreased amount XB13580952 [provisional] expression in the embryo

decreased amount XB22062454 [provisional] expression in the embryo

decreased amount XB5717875 [provisional:plac8] expression in the embryo

increased amount XB5717875 [provisional:plac8] expression in the embryo

increased amount XB5759442 expression in the embryo

decreased amount XB5796700 [provisional:trim7] expression in the embryo

increased amount XB5796700 [provisional:trim7] expression in the embryo

decreased amount XB5809687 [provisional] expression in the embryo

decreased amount XB5815362 [provisional:cyp2j6] expression in the embryo

decreased amount XB5824245 [provisional:rergl] expression in the embryo

decreased amount XB5846730 [provisional:nnmt] expression in the embryo

increased amount XB5901519 [provisional:tprg1l] expression in the embryo

decreased amount XB5901519 [provisional:tprg1l] expression in the embryo

decreased amount XB5961731 [provisional:ins] expression in the embryo

increased amount XB5962542 [provisional] expression in the embryo

decreased amount XB5994589 [provisional] expression in the embryo

decreased amount XB994119 [provisional:atp8b2] expression in the embryo

increased amount XB994119 [provisional:atp8b2] expression in the embryo

decreased amount xbp1 expression in the embryo

decreased amount xmc expression in the embryo

decreased amount zeb2 expression in the embryo

increased amount zfp36 expression in the embryo

decreased amount zfp36 expression in the embryo

decreased amount zic3 expression in the embryo

decreased amount zic4 expression in the embryo

decreased amount znf219 expression in the embryo

GEO Series: GSE113186: Xenbase, NCBI

Article: XB-ART-56302, PubMed