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XB-PHENO-25161

Xtr Wt + SB431542 + LDN-193189, Gentsch GE et al. (2019)

Experiment + Assay: Xtr Wt + SB431542 + LDN-193189 + NF9 (RNA-Seq)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical SB431542
NF stage 4 (8-cell) embryo
chemical 1062368-24-4
NF stage 4 (8-cell) embryo
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 9  
Expression Phenotypes (84):
decreased amount avp expression in the embryo
decreased amount bix1.1 expression in the embryo
decreased amount bix1.2 expression in the embryo
decreased amount cer1 expression in the embryo
decreased amount cfd expression in the embryo
decreased amount chrd.1 expression in the embryo
decreased amount cmtm8 expression in the embryo
decreased amount dkk1 expression in the embryo
decreased amount dkkx expression in the embryo
decreased amount efnb2 expression in the embryo
decreased amount eomes expression in the embryo
decreased amount epha4 expression in the embryo
decreased amount fgf16 expression in the embryo
decreased amount flrt3 expression in the embryo
decreased amount foxa4 expression in the embryo
decreased amount foxc1 expression in the embryo
decreased amount frzb2 expression in the embryo
decreased amount frzb expression in the embryo
decreased amount fst expression in the embryo
decreased amount fzd8 expression in the embryo
decreased amount gata2 expression in the embryo
decreased amount gata4 expression in the embryo
decreased amount gata5 expression in the embryo
decreased amount gata6 expression in the embryo
decreased amount gpr82 expression in the embryo
decreased amount gsc expression in the embryo
decreased amount h2bc14 expression in the embryo
increased amount hesx1 expression in the embryo
decreased amount hesx1 expression in the embryo
decreased amount hhex expression in the embryo
decreased amount igf2 expression in the embryo
decreased amount lefty expression in the embryo
decreased amount lhx1 expression in the embryo
decreased amount LOC100485974 expression in the embryo
decreased amount LOC100486013 expression in the embryo
decreased amount LOC100491743 expression in the embryo
decreased amount LOC100496394 expression in the embryo
decreased amount LOC101733394 expression in the embryo
decreased amount LOC101733442 expression in the embryo
decreased amount LOC101734579 expression in the embryo
decreased amount LOC105945931 expression in the embryo
decreased amount LOC105948225 expression in the embryo
decreased amount LOC116408047 expression in the embryo
increased amount LOC116408399 expression in the embryo
increased amount LOC116408477 expression in the embryo
decreased amount LOC116411062 expression in the embryo
decreased amount lrrc75b expression in the embryo
decreased amount mertk expression in the embryo
decreased amount mespa expression in the embryo
decreased amount mespb expression in the embryo
decreased amount mix1 expression in the embryo
decreased amount mixer expression in the embryo
decreased amount mmp1 expression in the embryo
decreased amount nodal1 expression in the embryo
increased amount nodal2 expression in the embryo
decreased amount nodal2 expression in the embryo
decreased amount nrp2 expression in the embryo
decreased amount osr1 expression in the embryo
decreased amount osr2 expression in the embryo
decreased amount otx2 expression in the embryo
decreased amount pcdh7 expression in the embryo
decreased amount pcdh8.2 expression in the embryo
decreased amount pdgfra expression in the embryo
decreased amount pecam1 expression in the embryo
decreased amount phox2b expression in the embryo
decreased amount pitx2 expression in the embryo
decreased amount pkdcc.2 expression in the embryo
decreased amount plekhg5 expression in the embryo
decreased amount plekho1 expression in the embryo
decreased amount sebox expression in the embryo
decreased amount six1 expression in the embryo
decreased amount sla expression in the embryo
decreased amount slc12a3l expression in the embryo
decreased amount slc3a1 expression in the embryo
decreased amount slc6a8 expression in the embryo
decreased amount sowahc expression in the embryo
decreased amount sox17a expression in the embryo
decreased amount spns2 expression in the embryo
decreased amount spry4 expression in the embryo
decreased amount ssh2 expression in the embryo
decreased amount st3gal1 expression in the embryo
decreased amount tfap2e expression in the embryo
decreased amount tmcc1 expression in the embryo
decreased amount vcan expression in the embryo
GEO Series: GSE122551: Xenbase, NCBI
Article: XB-ART-56693, PubMed