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XB-PHENO-25490

Xla Wt + shroom3 MO, Kowalczyk I et al. (2021)

Experiment + Assay: Xla Wt + shroom3 MO + NF16 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection shroom3 MO1 shroom3 (Xla)
 NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 16  
Anatomical Phenotypes: abnormal apical constriction , abnormal neural tube closure , abnormal neural tube morphology
Expression Phenotypes (1):
decreased amount lrp2.L expression in neural plate
Source: Fig.6.A,A1,A2
Article: XB-ART-57750, PubMed