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XB-PHENO-25549

Xla Wt + sobp CRISPR, Tavares ALP et al. (2021)

Experiment + Assay: Xla Wt + sobp CRISPR + NF28-33/34 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR sobp gRNA1 sobp (Xla)
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28 to NF stage 33 and 34  
Anatomical Phenotypes: decreased size of the otic vesicle
Expression Phenotypes (3):
decreased amount dlx5.L expression in otic vesicle
decreased amount pax2.L expression in otic vesicle
decreased amount six1.L expression in otic vesicle
Source: Fig.5.D,G,J
Article: XB-ART-58292, PubMed