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XB-PHENO-25755

Xla Wt + ints13 MO, Mascibroda LG et al. (2022)

Experiment + Assay: Xla Wt + ints13 MO + NF28 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection ints13 MO2 ints13 (Xla)
NF stage 2 (2-cell) non-neural ectoderm
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28  
Anatomical Phenotypes: abnormal main body axis , decreased size of the head , delayed embryo development , increased size of the endoderm , increased size of the foregut
Human Disease Associations: ciliopathy
Source: Fig. 7b, r1c2
Article: XB-ART-59396, PubMed