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XB-PHENO-25848

Xtr Wt + hif1a MO NF2, Patel JH et al. (2022)

Experiment + Assay: Xtr Wt + hif1a MO NF2 + NF18 (in situ hybridization)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection hif1a MO3 hif1a
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 18  
Anatomical Phenotypes: abnormal cranial neural crest morphology , decreased cell migration in branchial crest , decreased cell migration in cranial neural crest , decreased cell migration in hyoid crest , decreased cell migration in mandibular crest
Source: Fig. 5A
Article: XB-ART-58820, PubMed