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XB-PHENO-25914

Xla WT + ssbp2 MO, Cervino AS et al. (2023)

Experiment + Assay: Xla WT + ssbp2 MO + NF32 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection ssbp2 MO1 ssbp2 (Xla)
 NF stage 2 (2-cell) animal pole
lineage tracer ssbp2-eGFP mRNA
NF stage 2 (2-cell) animal pole
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 32  
Anatomical Phenotypes: abnormal development of pronephric duct , abnormal development of pronephric kidney , abnormal pronephric tubule morphology , decreased size of the pronephric tubule
Expression Phenotypes (3):
decreased amount hoxb7.L expression in pronephric kidney
decreased amount lhx1.L expression in proximal tubule
decreased amount pax8.L expression in proximal tubule
Source: Fig S5. e j o p
Article: XB-ART-60322, PubMed