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XB-PHENO-25945

Xla.Tg(mbp:GFP-NTR) + MTZ, Nguyen LT et al. (2023)

Experiment + Assay: Xla.Tg(mbp:GFP-NTR) + MTZ + NF55 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical metronidazole
NF stage 50 whole organism
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 55  
Expression Phenotypes (1):
decreased amount mbp.L expression in optic nerve
Human Disease Associations: multiple sclerosis
Source: Fig. 9 A.iii iv, C
Article: XB-ART-60406, PubMed