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XB-PHENO-26033

Xla Wt + pax2 MO3, Buisson I et al. (2015)

Experiment + Assay: Xla Wt + pax2 MO3 + NF33/34-35/36 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection pax2 MO3 pax2.L
pax2.S
NF stage 3 (4-cell) left blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 33 and 34 to NF stage 35 and 36  
Expression Phenotypes (9):
decreased amount atp1b1.S expression in proximal tubule
decreased amount cimap1a.L expression in pronephric nephrostome
absent clcnkb.L expression in pronephric duct
absent clcnkb.L expression in pronephric kidney
decreased amount cldn19.L expression in proximal tubule
decreased amount mecom.L expression in proximal tubule
decreased amount pax2.L expression in proximal tubule
decreased amount rgn.L expression in glomus
decreased amount slc12a1.L expression in proximal tubule
Source: Sup.Fig. S2 A a-k
Article: XB-ART-49971, PubMed