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XB-PHENO-26298

Xla Wt + tbp KD+ tbpl2 KD+ tbpl1 KD, Gazdag E et al. (2016)

Experiment + Assay: Xla Wt + tbp KD+ tbpl2 KD+ tbpl1 KD + WE NF10-10.5 - RNA-Seq (RNA)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
DMED injection tbp.L tbp.L
 NF stage 1 blastomere
DMED injection tbpl1.L tbpl1.L
 NF stage 1 blastomere
DMED injection tbpl2.L tbpl2.L
 NF stage 1 blastomere
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 10 to NF stage 10.5  
Expression Phenotypes (450):
decreased amount a2ml1.L expression in the embryo
decreased amount a2m.S expression in the embryo
decreased amount abca3.L expression in the embryo
decreased amount abcb6.L expression in the embryo
decreased amount abcg2.S expression in the embryo
increased amount acod1lb.L expression in the embryo
decreased amount acod1lb.L expression in the embryo
increased amount acot13.S expression in the embryo
decreased amount adam13.L expression in the embryo
decreased amount adam17.S expression in the embryo
decreased amount adcy9.S expression in the embryo
decreased amount admp2.L expression in the embryo
decreased amount aff4.S expression in the embryo
decreased amount ahnak.L expression in the embryo
decreased amount ahnak.S expression in the embryo
decreased amount ak8.S expression in the embryo
decreased amount akap9.L expression in the embryo
decreased amount akap9.S expression in the embryo
decreased amount aldh1l1.L expression in the embryo
decreased amount ankhd1.L expression in the embryo
decreased amount ankrd17.L expression in the embryo
decreased amount ano9.L expression in the embryo
decreased amount ap5b1.L expression in the embryo
decreased amount apc.S expression in the embryo
decreased amount apmap.L expression in the embryo
decreased amount apoc1.L expression in the embryo
increased amount apoc1.L expression in the embryo
decreased amount araf.S expression in the embryo
decreased amount arfgef1.L expression in the embryo
decreased amount arfgef1.S expression in the embryo
decreased amount arfgef2.L expression in the embryo
decreased amount arg1.L expression in the embryo
increased amount arhgap11a.2.L expression in the embryo
decreased amount arhgap12.S expression in the embryo
decreased amount aspm.L expression in the embryo
decreased amount atad2b.L expression in the embryo
increased amount atf6b.S expression in the embryo
decreased amount atp1a1.L expression in the embryo
decreased amount axin2.L expression in the embryo
decreased amount baz2a.L expression in the embryo
increased amount bcl6.L expression in the embryo
decreased amount bdp1.S expression in the embryo
decreased amount bicd2l.L expression in the embryo
decreased amount birc2.S expression in the embryo
decreased amount birc6.S expression in the embryo
increased amount bix1.2.S expression in the embryo
decreased amount bltp1.L expression in the embryo
decreased amount blvra.L expression in the embryo
decreased amount bod1l1.S expression in the embryo
decreased amount bptf.S expression in the embryo
decreased amount btbd6.L expression in the embryo
decreased amount btbd7.S expression in the embryo
increased amount btg4.L expression in the embryo
increased amount btg5.1.L expression in the embryo
increased amount c3.L expression in the embryo
decreased amount c3.L expression in the embryo
increased amount c6h8orf88.L expression in the embryo
decreased amount c8g.S expression in the embryo
decreased amount ca7.L expression in the embryo
decreased amount cabin1.L expression in the embryo
decreased amount cad.L expression in the embryo
decreased amount camsap2.L expression in the embryo
decreased amount capn15.L expression in the embryo
decreased amount capn8.1.L expression in the embryo
decreased amount capn8.1.S expression in the embryo
increased amount cbx4.S expression in the embryo
increased amount ccdc126.S expression in the embryo
decreased amount cchcr1.L expression in the embryo
decreased amount cdc42bpb.L expression in the embryo
increased amount cdc7.L expression in the embryo
decreased amount cdh1.S expression in the embryo
decreased amount cdk5r1.S expression in the embryo
decreased amount cdx2.L expression in the embryo
decreased amount cdx4.L expression in the embryo
decreased amount cdx4.S expression in the embryo
decreased amount cebpa.L expression in the embryo
increased amount cebpd.S expression in the embryo
decreased amount cebpd.S expression in the embryo
decreased amount celsr2.L expression in the embryo
decreased amount cenpf.L expression in the embryo
decreased amount cep170b.S expression in the embryo
increased amount chac1.S expression in the embryo
decreased amount chd4.L expression in the embryo
decreased amount ckb.S expression in the embryo
increased amount ckb.S expression in the embryo
decreased amount clca3p.L expression in the embryo
increased amount clip4.L expression in the embryo
decreased amount cltc.S expression in the embryo
decreased amount coa3.L expression in the embryo
decreased amount cog3.L expression in the embryo
increased amount commd6.L expression in the embryo
decreased amount copb1.S expression in the embryo
decreased amount copb2.L expression in the embryo
decreased amount copb2.S expression in the embryo
decreased amount cpox.L expression in the embryo
increased amount crlf1.L expression in the embryo
increased amount crygdl.4.L expression in the embryo
decreased amount crygdl.4.L expression in the embryo
decreased amount csnk1d.L expression in the embryo
decreased amount ctps1.S expression in the embryo
decreased amount cyfip1.L expression in the embryo
decreased amount cyfip1.S expression in the embryo
decreased amount cyp27c1.S expression in the embryo
decreased amount darmin.L expression in the embryo
decreased amount dbr1.L expression in the embryo
decreased amount dbr1.S expression in the embryo
decreased amount ddx39a.L expression in the embryo
decreased amount ddx39b.L expression in the embryo
decreased amount ddx46.L expression in the embryo
decreased amount degs3.L expression in the embryo
decreased amount dhh.L expression in the embryo
decreased amount dhh.S expression in the embryo
decreased amount dhx15.L expression in the embryo
decreased amount diaph1.L expression in the embryo
decreased amount dlx3.S expression in the embryo
decreased amount dnah9.S expression in the embryo
decreased amount dock1.S expression in the embryo
decreased amount dop1b.L expression in the embryo
decreased amount drosha.S expression in the embryo
decreased amount dync1h1.S expression in the embryo
decreased amount efcab6.S expression in the embryo
increased amount ehbp1.L expression in the embryo
decreased amount ehbp1.L expression in the embryo
decreased amount eif4g1.S expression in the embryo
decreased amount elapor2.L expression in the embryo
decreased amount elapor2.S expression in the embryo
decreased amount elovl3.L expression in the embryo
increased amount emc9.L expression in the embryo
decreased amount eml4.S expression in the embryo
decreased amount enah.L expression in the embryo
decreased amount eps8l3.S expression in the embryo
decreased amount ercc6.L expression in the embryo
decreased amount ern1.L expression in the embryo
decreased amount exd3.L expression in the embryo
decreased amount eya2.L expression in the embryo
increased amount fam110b.S expression in the embryo
decreased amount fam50a.S expression in the embryo
decreased amount fam83h.S expression in the embryo
decreased amount fat1.L expression in the embryo
decreased amount fbp1.L expression in the embryo
decreased amount fcgbp.L expression in the embryo
increased amount fgd3.L expression in the embryo
decreased amount fibcd1.S expression in the embryo
decreased amount flna.S expression in the embryo
decreased amount fn1.L expression in the embryo
decreased amount fn3k.L expression in the embryo
decreased amount foxa2.S expression in the embryo
decreased amount foxi1.S expression in the embryo
decreased amount fry.L expression in the embryo
decreased amount fth1.2.L expression in the embryo
increased amount fut11.S expression in the embryo
decreased amount fzd4.L expression in the embryo
decreased amount gak.S expression in the embryo
decreased amount gapvd1.S expression in the embryo
decreased amount gas1.L expression in the embryo
decreased amount gata5.S expression in the embryo
decreased amount gatm.L expression in the embryo
decreased amount gatm.S expression in the embryo
decreased amount gby.L expression in the embryo
decreased amount gcc2.S expression in the embryo
decreased amount gcn1.L expression in the embryo
decreased amount gfpt1.S expression in the embryo
decreased amount gfpt2.L expression in the embryo
decreased amount ggt1.L expression in the embryo
decreased amount gjb1.L expression in the embryo
decreased amount gjb2.L expression in the embryo
increased amount glt1d1.L expression in the embryo
decreased amount gnb3.L expression in the embryo
decreased amount gprc5b.L expression in the embryo
decreased amount greb1l.L expression in the embryo
decreased amount gsc.L expression in the embryo
decreased amount hao1.L expression in the embryo
decreased amount has-rs.S expression in the embryo
decreased amount hdac8.L expression in the embryo
decreased amount heatr5a.L expression in the embryo
decreased amount heatr5b.L expression in the embryo
decreased amount herc1.L expression in the embryo
increased amount herc1.L expression in the embryo
decreased amount hes5.1.L expression in the embryo
increased amount hes5.1.L expression in the embryo
decreased amount hes5.5.S expression in the embryo
decreased amount hes5.6.L expression in the embryo
decreased amount hes5.7.L expression in the embryo
decreased amount hes5.9.L expression in the embryo
decreased amount hes6.1.L expression in the embryo
decreased amount hif1a.L expression in the embryo
decreased amount hmcn2.L expression in the embryo
increased amount hmgcs1.S expression in the embryo
decreased amount hnf1b.L expression in embryo
decreased amount hnrnpab.L expression in the embryo
decreased amount hnrnpm.L expression in the embryo
decreased amount hook2.L expression in the embryo
decreased amount hoxd1.L expression in the embryo
decreased amount hsph1.S expression in the embryo
increased amount hwa.L expression in the embryo
increased amount hycc2.S expression in the embryo
decreased amount igf2r.L expression in the embryo
increased amount igf3.L expression in the embryo
decreased amount ikbke.S expression in the embryo
decreased amount ikbkg.L expression in the embryo
decreased amount il6st.L expression in the embryo
decreased amount inka1.S expression in the embryo
decreased amount inpp5b.L expression in the embryo
decreased amount inppl1a.L expression in the embryo
decreased amount ints1.L expression in the embryo
increased amount isca2.L expression in the embryo
decreased amount itgb1.L expression in the embryo
decreased amount jmjd6.S expression in the embryo
increased amount josd1.L expression in the embryo
increased amount jpt1.S expression in the embryo
decreased amount kat14.L expression in the embryo
decreased amount kcne5.L expression in the embryo
decreased amount kcnk6.S expression in the embryo
decreased amount kcnq1.L expression in the embryo
decreased amount kdm1a.S expression in the embryo
decreased amount kif22.L expression in the embryo
decreased amount kif22.S expression in the embryo
decreased amount kif26a.S expression in the embryo
decreased amount kif2a.S expression in the embryo
decreased amount kifap3.S expression in the embryo
decreased amount krt12.4.L expression in embryo
decreased amount krt12.4.S expression in the embryo
decreased amount krt12.5.S expression in the embryo
decreased amount krt70.L expression in the embryo
decreased amount krt7.L expression in the embryo
decreased amount krt7.S expression in the embryo
decreased amount krt8.1.S expression in the embryo
decreased amount lamb1.L expression in the embryo
decreased amount larp7.L expression in the embryo
increased amount leprot.S expression in the embryo
decreased amount lig3.L expression in the embryo
decreased amount lrba.L expression in the embryo
decreased amount lrp4.L expression in the embryo
decreased amount lrrk2.L expression in the embryo
decreased amount lrrn1.L expression in the embryo
decreased amount lypd6.L expression in the embryo
decreased amount macf1.L expression in the embryo
decreased amount macf1.S expression in the embryo
decreased amount mast4.L expression in the embryo
increased amount mctp2.L expression in the embryo
increased amount mecr.S expression in the embryo
increased amount meis3.L expression in the embryo
decreased amount meis3.L expression in the embryo
decreased amount meis3.S expression in the embryo
increased amount mgc147117.S expression in the embryo
decreased amount mki67.S expression in the embryo
increased amount mknk1.S expression in the embryo
decreased amount mprip.L expression in the embryo
decreased amount mrpl37.L expression in the embryo
decreased amount mrps18a.L expression in the embryo
decreased amount msgn1.L expression in embryo
decreased amount msgn1.S expression in the embryo
decreased amount mst1.L expression in the embryo
decreased amount mtor.L expression in the embryo
increased amount mul1a.S expression in the embryo
decreased amount myf5.L expression in the embryo
increased amount mylip.S expression in the embryo
decreased amount naalad2.S expression in the embryo
decreased amount nars1.L expression in the embryo
decreased amount nat8.6.S expression in the embryo
increased amount nbas.L expression in the embryo
decreased amount nbas.L expression in the embryo
decreased amount nbeal1.L expression in the embryo
decreased amount ncoa3.L expression in the embryo
increased amount ndufa7.S expression in the embryo
decreased amount nefl.L expression in the embryo
decreased amount net1.S expression in the embryo
decreased amount nf1.L expression in the embryo
decreased amount nf1.S expression in the embryo
decreased amount nfasc.S expression in the embryo
increased amount nfe2l2.S expression in the embryo
decreased amount nodal1.L expression in embryo
increased amount nodal3.1.L expression in embryo
increased amount nodal3.2.L expression in the embryo
increased amount nodal5.2.L expression in the embryo
increased amount nodal5.L expression in the embryo
increased amount nodal6.L expression in the embryo
increased amount nppb.S expression in the embryo
increased amount nr2f2.L expression in the embryo
decreased amount nr6a1.L expression in the embryo
decreased amount nup98l.L expression in the embryo
decreased amount nup98l.S expression in the embryo
decreased amount nxpe3l.6.L expression in the embryo
decreased amount ogdh.S expression in the embryo
decreased amount olig4.L expression in the embryo
increased amount oxr1.S expression in the embryo
increased amount pank2.S expression in the embryo
increased amount park7.S expression in the embryo
decreased amount pcnt.L expression in the embryo
decreased amount pcnx1.L expression in the embryo
decreased amount pdhb.L expression in the embryo
decreased amount pet100.L expression in the embryo
increased amount pet100.L expression in the embryo
decreased amount pex6.S expression in the embryo
decreased amount phactr4.S expression in the embryo
decreased amount phkb.S expression in the embryo
increased amount pigf.S expression in the embryo
decreased amount pigk.S expression in the embryo
increased amount pim3.L expression in the embryo
increased amount pim3.S expression in the embryo
decreased amount pkd1l1.L expression in the embryo
increased amount plpp6.S expression in the embryo
decreased amount post3.S expression in the embryo
decreased amount post.L expression in the embryo
decreased amount ppip5k2.L expression in the embryo
increased amount ppp1cc.L expression in the embryo
increased amount prdx2.L expression in the embryo
decreased amount prmt9.L expression in the embryo
decreased amount proser1.S expression in the embryo
decreased amount prrc2b.L expression in the embryo
decreased amount prrc2b.S expression in the embryo
decreased amount psmd11.L expression in the embryo
decreased amount psmd11.S expression in the embryo
decreased amount psmd1.L expression in the embryo
decreased amount ptgs2.S expression in the embryo
decreased amount qsox1.L expression in the embryo
decreased amount ranbp2.L expression in the embryo
decreased amount rapgef6.S expression in the embryo
decreased amount raver1.L expression in the embryo
decreased amount raver1.S expression in the embryo
decreased amount rbfox2.L expression in the embryo
decreased amount rbfox2.S expression in the embryo
decreased amount rbm17.L expression in the embryo
decreased amount rbm47.L expression in the embryo
increased amount rbp1.L expression in the embryo
decreased amount rdd4.L expression in the embryo
decreased amount rdh16.2.L expression in the embryo
decreased amount rfk.S expression in the embryo
decreased amount rhebl1.L expression in the embryo
increased amount rnasek.S expression in the embryo
decreased amount rnf157.L expression in the embryo
increased amount rnf180.S expression in the embryo
decreased amount rngtt.S expression in the embryo
decreased amount ror2.S expression in the embryo
decreased amount rpe65.S expression in the embryo
decreased amount rpl27.L expression in the embryo
decreased amount rps21.L expression in the embryo
decreased amount rps9.L expression in the embryo
decreased amount rps9.S expression in the embryo
decreased amount rrm2.L expression in the embryo
decreased amount sacm1l.L expression in the embryo
decreased amount sbf2.L expression in the embryo
decreased amount sbf2.S expression in the embryo
decreased amount scaf11.L expression in the embryo
decreased amount scaf11.S expression in the embryo
decreased amount scp2.L expression in the embryo
increased amount scp2.L expression in the embryo
decreased amount sds.L expression in the embryo
decreased amount sec16a.S expression in the embryo
decreased amount selenoo.L expression in the embryo
decreased amount sf3b1.S expression in the embryo
decreased amount sia1.L expression in embryo
increased amount sia1.L expression in embryo
decreased amount sipa1l1.L expression in the embryo
decreased amount slc12a4.L expression in the embryo
increased amount slc15a4.S expression in the embryo
decreased amount slc15a4.S expression in the embryo
decreased amount slc16a10.S expression in the embryo
decreased amount slc22a15.2.S expression in the embryo
decreased amount slc27a4.S expression in the embryo
decreased amount slc28a3.L expression in the embryo
decreased amount slc2a2.L expression in the embryo
decreased amount slc30a8.L expression in the embryo
decreased amount slc35a1.L expression in the embryo
decreased amount slc39a8.L expression in the embryo
decreased amount slc4a7.L expression in the embryo
decreased amount slc6a8.L expression in the embryo
decreased amount slc6a8.S expression in the embryo
decreased amount slk.L expression in the embryo
decreased amount smg1.L expression in the embryo
decreased amount socs3.S expression in the embryo
increased amount socs3.S expression in the embryo
decreased amount son.S expression in the embryo
increased amount spsb1.S expression in the embryo
increased amount sptbn1.L expression in the embryo
decreased amount sri.L expression in the embryo
increased amount sri.L expression in the embryo
decreased amount ssr3.L expression in the embryo
decreased amount stk40.L expression in the embryo
increased amount stx11.S expression in the embryo
decreased amount stxbp6.L expression in the embryo
decreased amount supt20h.S expression in the embryo
increased amount swsap1.L expression in the embryo
increased amount sybu.L expression in the embryo
increased amount sybu.S expression in the embryo
decreased amount szl.L expression in the embryo
decreased amount tarbp2.S expression in the embryo
decreased amount tasor2.S expression in the embryo
decreased amount tbc1d13.L expression in the embryo
decreased amount tbc1d13.S expression in the embryo
increased amount tbccd1.L expression in the embryo
decreased amount tbxt.L expression in embryo
decreased amount tdrd9.L expression in the embryo
decreased amount tead4.L expression in the embryo
increased amount tert.L expression in the embryo
decreased amount thumpd1.S expression in the embryo
decreased amount tll1.S expression in the embryo
increased amount tm2d3.S expression in the embryo
increased amount tmem199.L expression in the embryo
decreased amount tmem72.L expression in the embryo
decreased amount tnfsf10l.L expression in the embryo
decreased amount tnpo1.S expression in the embryo
decreased amount top2b.L expression in the embryo
decreased amount tp53bp1.L expression in the embryo
decreased amount tp53bp1.S expression in the embryo
decreased amount tpp2.L expression in the embryo
decreased amount trim29.L expression in the embryo
increased amount tsfml.S expression in the embryo
decreased amount tspan8.L expression in the embryo
decreased amount tuba1cl.2.S expression in the embryo
decreased amount tuba1cl.3.L expression in the embryo
decreased amount uap1.S expression in the embryo
decreased amount ubac1.L expression in the embryo
decreased amount ubac1.S expression in the embryo
decreased amount ubqln4.S expression in the embryo
decreased amount ufl1.L expression in the embryo
decreased amount unc93a.2.L expression in the embryo
decreased amount usp10.S expression in the embryo
increased amount usp12b.L expression in the embryo
decreased amount usp14.L expression in the embryo
decreased amount usp24.L expression in the embryo
decreased amount usp24.S expression in the embryo
decreased amount usp34.S expression in the embryo
decreased amount usp4.L expression in the embryo
decreased amount utrn.L expression in the embryo
decreased amount val.L expression in the embryo
decreased amount vepp1.L expression in the embryo
decreased amount vps50.L expression in the embryo
decreased amount vrk3.L expression in the embryo
decreased amount wdfy4.L expression in the embryo
decreased amount wfdc2.L expression in the embryo
decreased amount wnt5b.L expression in the embryo
decreased amount XB1001290.L expression in the embryo
decreased amount XB22041731.S [provisional] expression in the embryo
decreased amount XB22062450.L expression in the embryo
decreased amount XB22062450.S expression in the embryo
decreased amount XB22063249.S expression in the embryo
increased amount XB22063314.L [provisional:yrdc] expression in the embryo
increased amount XB22065716.L [provisional] expression in the embryo
increased amount XB5796436.S expression in the embryo
decreased amount xbp1.S expression in the embryo
decreased amount xepsin.L expression in the embryo
decreased amount xpo1.S expression in the embryo
decreased amount yrdcl.L expression in the embryo
decreased amount ythdc2.L expression in the embryo
increased amount zbtb18.S expression in the embryo
increased amount zfand1.L expression in the embryo
increased amount zfand2a.L expression in the embryo
increased amount zfp36l2.1.L expression in the embryo
increased amount zftraf1.S expression in the embryo
GEO Series: GSE76994: Xenbase, NCBI
Article: XB-ART-51942, PubMed