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XB-PHENO-26953

Xtr Wt + acbd6 CRISPR (68), Kaiyrzhanov R et al. (2024)

Experiment + Assay: Xtr Wt + acbd6 CRISPR (68) + NF45 (stained tissue microscopy)
Background: Xtr.Nigerian1EXRC
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR acbd6 gRNA1 acbd6
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
stained tissue microscopy NF stage 45  
Anatomical Phenotypes: abnormal chondrocranium , abnormal oropharynx , abnormal pharyngeal region , decreased size of the head
Human Disease Associations: microcephaly
Source: Fig. 5 EF
Article: XB-ART-60415, PubMed