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XB-PHENO-26989

Xla Wt + htra1, Pera EM et al. (2024)

Experiment + Assay: Xla Wt + htra1 + NF41 (in situ hybridization)
Background: Xla.albino
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection htra1 (Xla) htra1 (Xla)
 NF stage 4 (8-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 41  
Anatomical Phenotypes: abnormal cartilage tissue , abnormal ceratobranchial I morphology , abnormal ethmoid region , decreased size of the ceratohyal , decreased size of the head , decreased size of the Meckel's cartilage
Expression Phenotypes (2):
decreased amount sox9.L expression in branchial basket
decreased amount sox9.L expression in ethmoid region
Source: Fig. 4 B B'
Article: XB-ART-60672, PubMed