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XB-PHENO-27126

Xla Wt + nodal1 + ctnnb1 MO, Azbazdar Y and De Robertis EM (2024)

Experiment + Assay: Xla Wt + nodal1 + ctnnb1 MO + NF33/34 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection nodal1 (Xla) nodal1 (Xla)
NF stage 3 (4-cell) left-ventral blastomere
morpholino injection ctnnb1 MO1 ctnnb1 (Xla)
NF stage 3 (4-cell) whole organism
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 33 and 34  
Anatomical Phenotypes: abnormal foregut , abnormal head , abnormal ventral side , increased size of the cement gland , increased size of the head region
Source: Fig. 2 DEF
Article: XB-ART-60778, PubMed