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XB-PHENO-27135

Xla Wt + szl MO, Azbazdar Y and De Robertis EM (2024)

Experiment + Assay: Xla Wt + szl MO + NF28 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection szl MO1 szl (Xla)
 NF stage 3 (4-cell) whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28  
Anatomical Phenotypes: abnormal ventral side , absent tail , absent tail bud , decreased size of the head , partially ventralized embryo
Expression Phenotypes (2):
decreased amount sox2.L expression in brain
decreased amount sox2.L expression in eye
Source: Fig. 5 F'
Article: XB-ART-60778, PubMed