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XB-PHENO-27137

Xla Wt + dkk1, Azbazdar Y and De Robertis EM (2024)

Experiment + Assay: Xla Wt + dkk1 + NF28 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection dkk1 (Xla) dkk1 (Xla)
 NF stage 3 (4-cell) whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28  
Anatomical Phenotypes: abnormal head , abnormal tail , abnormal trunk somite , partially dorsalized embryo
Expression Phenotypes (1):
increased amount sox2.L expression in brain
Source: Fig. 5 C'
Article: XB-ART-60778, PubMed