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XB-PHENO-27153

Xla Wt + barhl1 MO, Bou-Rouphael J et al. (2024)

Experiment + Assay: Xla Wt + barhl1 MO + NF45 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection barhl1 MO1 barhl1.L
 NF stage 4 (8-cell)
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 45  
Expression Phenotypes (5):
increased amount atoh1.L expression in granule cell layer of the cerebellum
increased amount atoh1.L expression in rhombic lip
decreased amount neurod1.L expression in rhombomere R1
absent pax6.L expression in granule cell layer of the cerebellum
absent pax6.L expression in rhombomere R1
Source: Fig 3 A a' a""B C D a
Article: XB-ART-60787, PubMed