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XB-PHENO-27260

Xtr Wt + sf3b4 CRISPR, Griffin C et al. (2025)

Experiment + Assay: Xtr Wt + sf3b4 CRISPR + NF40 (in situ hybridization)
Background: Xtr.Nigerian1NXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR sf3b4 gRNA1 sf3b4
 NF stage 1 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 40  
Expression Phenotypes (3):
decreased amount runx2 expression in head region
absent runx2 expression in pharyngeal arch
decreased amount sox9 expression in pharyngeal arch
Source: Fig. 5 A
Article: XB-ART-61310, PubMed