Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.icam5em2Horb | X. tropicalis | icam5 | 2nd Xtropicalis line with CRISPR knockout of icam5 (intercellular adhesion molecule 5), Germ line tr... | NXR |
| Xtr.hs6st1emNXR | X. tropicalis | hs6st1 | CRISPR knockout of hs6st1 (heparan sulfate 6-O-sulfotransferase 1) gene. Mutation not yet characteri... | NXR |
| Xtr.gdf1em3Horb | X. tropicalis | gdf1 | CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom m... | NXR |
| Xla.dmrt1em4NXR | X. laevis | dmrt1.L dmrt1.S | Double X. levis CRISPR knockout line, targeting both dmrt1.S and dmrt1.L (doublesex and mab-3 relat... | NXR |
| Xtr.cbsemNXR | X. tropicalis | cbs | Custom CRISPR generated by NXR, targeting the cbs (cystathionine-beta-synthase) gene, | NXR |
| Xtr.snai2em3NXR | X. tropicalis | snai2 | 3rd CRISPR knockout line targeting snai2 (snail family zinc finger 2) in X. tropicalis. Germ line tr... | NXR |
| Xtr.snai2 em2NXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | NXR |
| Xtr.sobp[em2NXR] | X. tropicalis | sobp | 2nd of 2 CRISPR knockout of sobp (sine oculis binding protein homolog ) X. tropicalis lines held by ... | NXR |
| Xtr.syngap1 emNXR | X. tropicalis | syngap1 | CRISPR line targeting syngap1 (). Not screened for mutation or germ line transmission yet. Contact t... | NXR |
| Xla.tcf3emNXR | X. laevis | tcf3.L | X. laevis CRISPR line targeting tcf3.L (transcription factor 3). Line in development. Contact NXR f... | NXR |
| Xla.tbx21emNXR | X. laevis | tbx21.L tbx21.S | double CRISPR KO line targeting tbx21.L and tbx21.S in X. laevis. germ line transmission snd mutatio... | NXR |
| Xla.tap2emNXR | X. laevis | tap2.L tap2.S | X. laevis CRISPR line targeting tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP), a... | NXR |
| Xla.tap1emNXR | X. laevis | tap1.L | X. laevis CRISPR line targeting tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP), a... | NXR |
| Xla.tracemHorb | X. laevis | trac.S | X. laevis CRISPR line targeting trac.S (T cell receptor alpha constant), a gene associated with immu... | NXR |
| Xla.velo1emNXR | X. laevis | velo1.L | X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized . Germ lin... | NXR |
| Xla.wnt3em2NXR | X. laevis | wnt3.L | X. laevis CRISPR line targeting wnt3.L (Wnt family member 3). Germ line transmission not yet confirm... | |
| Xla.wnt3em1NXR | X. laevis | wnt3.S | X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission not yet confirm... | NXR |
| Xtr.wnt3em1NXR | X. tropicalis | wnt3 | CRISPR line targeting wnt3 (Wnt family member 3). Germ line transmission not yet confirmed, mutation... | NXR |
| Xtr.xbp1em2NXR | X. tropicalis | xbp1 | 2nd X. tropicalis CRISPR line for xbp1 (X-box binding protein 1, a gene assocaited with Major Affec... | NXR |
| Xtr.shroom3em2Horb | X. tropicalis | shroom3 | CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... | NXR |
| Xtr.ripply3em2NXR | X. tropicalis | ripply3 | 2nd of 2 ripply3 lines at the NXR, CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ l... | NXR |
| Xtr.prph2em2Horb | X. tropicalis | prph2 | 2nd X. tropicalis line with CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Co... | NXR |
| Xtr.pou4f1em2NXR | X. tropicalis | pou4f1 | Custom CRISPR Xtropicalis line carrying a single 1bp insertion in pou4f1 (POU class 4 homeobox 1) ge... | NXR |
| Xla.pkhd1em3Horb | X. laevis | pkhd1.L | 3rd of 3 X. laevis CRISPR lines for pkhd1 (ciliary IPT domain containing fibrocystin/polyductin) gen... | NXR |
| Xla.pkhd1em2Horb | X. laevis | pkhd1.L | CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... | NXR |
| Xla.pax7em3Horb | X. laevis | pax7.L pax7.S | 3rd Xlaevis pax7 mutant line at the NXR. CRISPR knockout of pax7 (paired box 7). Germ line transmiss... | NXR |
| Xla.pax7em2Horb | X. laevis | pax7.L pax7.S | CRISPR knockout of pax7 (paired box ). Germ line transmission confirmed. Animals carry a -22bp dele... | NXR |
| Xtr.notch4 em2Horb | X. tropicalis | notch4 | the 2nd of 2 notch4 lines in X. tropicalis being bred by Horb lab. Contact NXR for details. | NXR |
| Xtr.nagluem3NXR) | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). 3rd of 3 X.tropicalis mutant lines. Germ ... | NXR |
| Xtr.eomesem2Horb | X. tropicalis | eomes | 2nd CRISPR knockout of eomes (eomesodermin), carrying a 4bp deletion. Custom mutant generated by Ho... | |
| Xtr.slc2a7tm,tyrtm,hps6tmHUARC | X. tropicalis | hps6 slc2a7 tyr | triple knock out (3KO) line generated by crossing mutant lines with KO of tyr, hps6, and slc2a7 | |
| Xtr.thratm,thrbtmShiyb | X. tropicalis | thra thrb | Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S... | |
| Xtr.tyremOchi | X. tropicalis | tyr | An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Ochi Lab. Th... | NBRP |
| Xtr.tyremKtsz | X. tropicalis | tyr | An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Suzuki Lab. ... | NBRP |
| Xtr.hps6emOgino | X. tropicalis | hps6 | CRISPR/Cas9-mediated targeted mutation in hsp6, a gene resonsible for X. tropicalis no privacy (nop)... | NBRP |
| Xla.pkd1em3Horb | X. laevis | pkd1.L | CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line ... | |
| Xla.pkd1em2Horb | X. laevis | pkd1.L | CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line ... | NXR |
| Xla.prkdcem2NXR | X. laevis | prkdc.L | CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission confi... | NXR |
| Xtr.bicc1em2NXR | X. tropicalis | bicc1 | CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... | |
| Xtr.staremNXR | X. tropicalis | star | CRISPR knockout of STAR (steroidogenic acute regulatory protein). Germ line transmission not yet con... | |
| Xtr.foxb1em2Horb | X. tropicalis | foxb1 | CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, germline transmission confirme... | |
| Xtr.gdf1em2Horb | X. tropicalis | gdf1 | CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ... | NXR |
| Xtr.acsl1emNXR | X. tropicalis | acsl1 | CRISPR knockout of acsl1 (acyl-CoA synthetase long chain family member 1). Germ line transmission co... | |
| Xtr.nagluem2NXR | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals... | NXR |
| Xtr.nagluem1NXR | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase) gene. Germ line transmission confirmed. An... | NXR |
| Xtr.lamp2em2NXR | X. tropicalis | lamp2 | CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme... | |
| Xtr.lamp2em1NXR | X. tropicalis | lamp2 | CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme... | |
| Xla.rag2emNXR | X. laevis | rag2.L | CRISPR knockout of rag2 (recombination activating 2). Germ line transmission confirmed. Animals carr... | NXR |
| Xtr.meis1emNXR | X. tropicalis | meis1 | CRISPR knockout of meis1 (meis homeobox 1). F0 growing, germline transmission not yet confirmed. | |
| Xla.rykemNXR | X. laevis | ryk.S | CRISPR knockout of ryk.S (receptor like tyrosine kinase S homeolog). Germline transmission not yet c... | NXR |
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