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XB-LINE-2038
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Line Name: Xla.pkd1em2Horb
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line transmission confirmed. F2 generation established and have a 17 bp deletion (AATAATAAAGT-----------------CCGAGGAGCTTCAGTTGA).Contact the NXR for details of mutation characterization. Custom mutant generated by Horb Lab. |
| Phenotype Description: | Embryos develop abnormal kidneys (dilated tubules appear after stage 40), cystic kidneys in F0s, |
| Color Morph: | albino |
| Breeding Type: | OUTBRED |
| Lab of Origin: | |
| Line Type: | Mutant |
| Mutated Gene(s): | pkd1.L |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | F2 | Order | |||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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