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XB-LINE-2268
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Line Name: Xla.pax7em2Horb
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | CRISPR knockout of pax7 (paired box). Germ line transmission confirmed. Animals carry a 22 base pair deletion in pax7.L and a 10 base pair deletion in pax7.S. Mutant line generated by Horb Lab. Contact the NXR for more details. |
| Phenotype Description: | -22 base pair mutation sequence on L allele GTGCAGGTACCAGGAGA----------------------CATCGGGGGCAGCAAA and -10 base pair mutation sequence on S allele GCAGGTACCAGGAGACTGGA----------CTGGGGCCATCGGGGG. Associated with human alveolar rhabdomyosarcoma. |
| Color Morph: | |
| Breeding Type: | OUTBRED |
| Lab of Origin: | Horb lab |
| Line Type: | Mutant |
| Mutated Gene(s): | pax7.L pax7.S |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2171 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2171 | F1 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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