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XB-LINE-2295
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Line Name: Xla.tbx21emNXR
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | Double CRISPR KO line targeting tbx21.L and tbx21.S in X. laevis. Germ line transmission confirmed. Animals carry a 4 base pair deletion on L allele and a 22 base pair deletion on the S allele. Contact the NXR for more details. |
| Phenotype Description: | -4 base pair mutation sequence on L allele GATGATCATTTC----TGGTGCTTGTGAAA and -22 base pair mutation sequence on S allele CCCTGCTTGGT----------------------TTGTGAAACTT. Associated with human asthma, nasal polyps, and aspirin intolerance. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | NXR |
| Line Type: | Mutant |
| Mutated Gene(s): | tbx21.L tbx21.S |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2163 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2163 | F0 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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