| Summary |
|
| Synonym: |
Elastase:TRDN-GFP; Elastase::TRDN-GFP3 |
| Species: |
Xenopus laevis |
| Background Strain: |
Xla.Outbred
|
| Paternal Line: |
|
| Maternal Line: |
|
| Description: |
205 bp rat (Rno) elastase (elas) promoter driving dominant negative (DN) form of the thyroid receptor alpha (thra) (aka TRDN), fused to GFP (fusion indictated by hyphen). pElastase-TRDN-GFP construct was coinjected with Xenopus gamma-crystallin GFP (from Grainger Lab) to produce this double transgenic line. |
| Phenotype Description: |
GFP expression in the pancreas (specifically in the nucleus of the acinar cells of NF54 tadpoles), and in lens. Exocrine pancreases of transgenic tadpoles expressing a dominant negative form of the Thyroid Hormone (TH) receptor controlled by the elastase promoter are resistant to TH. |
| Color Morph: |
|
| Breeding Type: |
OUTBRED
|
| Lab of Origin: |
Brown Lab |
| Line Type: |
Transgenic |
| Mutated Gene(s): |
|
| MTA Required: |
Yes
|
| Public: |
Yes
|
| Catalogue Number: |
waiting for EXRC RRID number |
