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XB-TRANSGENE-18373854
Transgene Name | Tg(caHsa.MAPK8) |
Description | A fusion construct incorporating human map2k7 and a c-terminal truncated mapk8 acting as a constitutively active form of mapk8. Also known as c.a.JNK, MKK7-JNK1, Tg(Flag-Mmu.map2k7-Hsa.mapk8) and Flag-MKK7-hJNK1. This fusion protein encodes an NH2-terminal epitope tag (Flag), residues 1 to 415 of JNK1/2 (deletion of 11 COOH-terminal amino acids), a short linker (Gly-Ser-Pro-Gly-Ile-Ser-Gly-Gly-Gly-Gly-Gly-Ile-Leu), and the complete sequence of MKK7b2. |
Inducibility | None |
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