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Fig. 4. Comparison of the expression
patterns of XHEN1, XLMO-3, XNGNR-
1 and N-tubulin. (A-J) Stage 14,
25 and 35 Xenopus embryos were
hybridized with probes for XLMO-3,
XHEN1, X-NGNR-1 and N-tubulin.
Embryos are shown in a dorsal (stage
14), dorsal-lateral (stage 25) or lateral
(stage 35) view, with anterior to the left.
At stage 14, XLMO-3 and XHEN1 are
expressed only in two domains which
will become interneurons (I) and
motoneurons (M) of spinal cord, while
X-NGNR-1 and N-tubulin are expressed
also in the domains which will form
sensory neurons (S) besides of these two
medial domains. At stage 25, the
expression patterns for all four probes
are very similar. At stage 35, XHEN1 is
only expressed in the brain region.
(K,L) Transverse sections of Xenopus
embryos hybridized with probes for
XHEN1 and XLMO-3 at stage 20. In the
neural tube, both of XHEN1 and
XLMO-3 are located in the ventral part
of spinal cord which is formed by
interneurons and motoneurons.