Fig. 4. Comparison of the expression patterns of XHEN1, XLMO-3, XNGNR- 1 and N-tubulin. (A-J) Stage 14, 25 and 35 Xenopus embryos were hybridized with probes for XLMO-3, XHEN1, X-NGNR-1 and N-tubulin. Embryos are shown in a dorsal (stage 14), dorsal-lateral (stage 25) or lateral (stage 35) view, with anterior to the left. At stage 14, XLMO-3 and XHEN1 are expressed only in two domains which will become interneurons (I) and motoneurons (M) of spinal cord, while X-NGNR-1 and N-tubulin are expressed also in the domains which will form sensory neurons (S) besides of these two medial domains. At stage 25, the expression patterns for all four probes are very similar. At stage 35, XHEN1 is only expressed in the brain region. (K,L) Transverse sections of Xenopus embryos hybridized with probes for XHEN1 and XLMO-3 at stage 20. In the neural tube, both of XHEN1 and XLMO-3 are located in the ventral part of spinal cord which is formed by interneurons and motoneurons.
Image published in: Bao J et al. (2000)
Copyright © 2000. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| nhlh1.L | bhlha35, hen-1, hen1, nhlh1-a, nhlh1-b, nscl, nscl1 | X. laevis | Throughout NF stage 14 | neural plate pre-chordal neural plate chordal neural plate motor neuron interneuron optic field neuroectoderm |
| tubb2b.L | NBT, neural beta-tubulin, NST, N-Tub, n-tubulin, ntubulin, Xn-tubulin | X. laevis | Throughout NF stage 14 | neuron Rohon-Beard neuron motor neuron interneuron spinal cord central nervous system brain neural plate pre-chordal neural plate chordal neural plate neural groove neural plate border neuroectoderm cranial placode neurogenic placode |
| neurog2.L | atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin2, neurogenin-related-1, ngn-2, ngn2, ngnr, Ngnr-1, Ngnr1, ngnr 1a, xngn2, X-ngnr-1, Xngnr-1, XNgnr1 | X. laevis | Throughout NF stage 14 | neural plate pre-chordal neural plate chordal neural plate central nervous system brain spinal cord neuron neurogenic placode neuroectoderm cranial placode |
| lmo1.L | bx, lmo-1, rbtn1, rhom1, rhombotin-1, rhombotin1, ttg1, xlmo-3 | X. laevis | Throughout NF stage 14 | neural plate pre-chordal neural plate chordal neural plate neural plate border neural progenitor cell neurogenic placode neuron Rohon-Beard neuron motor neuron interneuron optic field |
| nhlh1.L | bhlha35, hen-1, hen1, nhlh1-a, nhlh1-b, nscl, nscl1 | X. laevis | Throughout NF stage 20 | neural tube ventrolateral neural tube spinal cord |
| lmo1.L | bx, lmo-1, rbtn1, rhom1, rhombotin-1, rhombotin1, ttg1, xlmo-3 | X. laevis | Throughout NF stage 20 | neural tube posterior neural tube anterior neural tube ventrolateral neural tube somite sclerotome |
| nhlh1.L | bhlha35, hen-1, hen1, nhlh1-a, nhlh1-b, nscl, nscl1 | X. laevis | Throughout NF stage 25 | neural tube posterior neural tube anterior neural tube central nervous system brain spinal cord neuroectoderm optic vesicle eye forebrain midbrain hindbrain |
| tubb2b.L | NBT, neural beta-tubulin, NST, N-Tub, n-tubulin, ntubulin, Xn-tubulin | X. laevis | Throughout NF stage 25 | brain forebrain midbrain hindbrain neuron Rohon-Beard neuron motor neuron interneuron spinal cord neurogenic placode |
| neurog2.L | atoh4, neurog2-a, neurog2-b, neurogenin 2, neurogenin-2, neurogenin2, neurogenin-related-1, ngn-2, ngn2, ngnr, Ngnr-1, Ngnr1, ngnr 1a, xngn2, X-ngnr-1, Xngnr-1, XNgnr1 | X. laevis | Throughout NF stage 25 | brain forebrain midbrain hindbrain neuron Rohon-Beard neuron motor neuron interneuron spinal neuron neurogenic placode trigeminal placode spinal cord |
| lmo1.L | bx, lmo-1, rbtn1, rhom1, rhombotin-1, rhombotin1, ttg1, xlmo-3 | X. laevis | Throughout NF stage 25 | brain forebrain midbrain hindbrain spinal cord neuron Rohon-Beard neuron motor neuron interneuron neurogenic placode otic placode trigeminal placode optic vesicle |
| nhlh1.L | bhlha35, hen-1, hen1, nhlh1-a, nhlh1-b, nscl, nscl1 | X. laevis | Throughout NF stage 35 and 36 | brain eye cranial neural crest mandibular crest hyoid crest |
| lmo1.L | bx, lmo-1, rbtn1, rhom1, rhombotin-1, rhombotin1, ttg1, xlmo-3 | X. laevis | Throughout NF stage 35 and 36 | brain forebrain midbrain hindbrain spinal cord somite sclerotome dermomyotome |
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