Xenbase Image ID: 152319

Fig. S5. Expression analysis of Insulin/Insulin-like growth factor (Igf) signaling. Whole-mount in situ hybridizations and paraplast sections thereof comparing igf1 (A–B′′), igf3 (C–D′′), insulin receptor (insr) (E–F′′), insulin receptor substrate 1 (G–H′′), igf2 (I), insulin (ins) (K), igf receptor (igfr) (M), and insulin-related receptor (insrr) (N) at stages 34 (A, C, E, G, I, and K) and 38 (B–B′′, D–D′′, F–F′′, H–H′′, M, and N). (J and L) In situ hybridizations on paraplast sections of stage 42 Xenopus embryos for igf2 and insulin. Insets show sense control. Image published in: Romaker D et al. (2014) Copyright © 2014. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue igf3.L igf2, igf-3, LOC108697782 X. laevis Throughout NF stage 33 and 34 intermediate mesoderm pharyngeal region head tail lateral plate mesoderm insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Throughout NF stage 33 and 34 pronephric kidney proximal tubule head otic vesicle spinal cord pronephric duct irs1.S irs-1, LOC108718134 X. laevis Throughout NF stage 33 and 34 intermediate mesoderm pharyngeal region otic vesicle head igf2.L igf-2, igf2-a, igf2-b, IGF-II, insigf, pp9974 X. laevis Throughout NF stage 33 and 34 pronephric kidney proximal tubule liver primordium ins.L ins1, ins-a, ins-b, insulin, insulin I, preproinsulin, xins X. laevis Throughout NF stage 33 and 34 pronephric kidney proximal tubule spinal cord igf1.S igf-1, IGF-I, LOC108712492, Somatomedin, somatomedin-C, xigf1 X. laevis Throughout NF stage 37 and 38 liver igf3.L igf2, igf-3, LOC108697782 X. laevis Throughout NF stage 37 and 38 head intermediate mesoderm ectoderm lateral plate mesoderm insr.L cd220, hhf5, insulin receptor, Xe-InsR, XTK1, XTK1a, XTK1b X. laevis Throughout NF stage 37 and 38 pronephric kidney head proximal tubule pronephric duct pharyngeal region spinal cord irs1.S irs-1, LOC108718134 X. laevis Throughout NF stage 37 and 38 pronephric kidney head proximal tubule spinal cord ectoderm lateral plate mesoderm igf1r.L igf-1r, xIGF-1R, xigf1r, xIGFR, XTK2 X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric duct intermediate mesoderm tail head lateral plate mesoderm pharyngeal region spinal cord insrr.L insulin-related receptor, irr X. laevis Throughout NF stage 37 and 38 pronephric kidney proximal tubule myeloid cell Image source: Published Larger Image Printer Friendly View

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