Xenbase Image ID: 45194

Fig. 1. Spatiotemporal expression of podocyte genes. (A-A′) Schematics depicting the glomus (black) in whole Xenopus embryos (A) and in transverse section at low (A′) and high (A′) magnification at stage 35. (B-J′) In situ hybridization of podocyte transcription factors wt1 (B-B′), foxc2 (C-C′), tcf21 (D-D′), mafb (E-E′) and lmx1b (F-F′) and of markers of podocyte differentiation kirrel (G-G′), nphs1 (H-H′), ptpru (I-I′) and nphs2 (J-J′) at stage 35 in whole-mounts (B-J) and transverse sections (B′-J′). (K) Temporal profile of podocyte gene expression in the glomus. en, endoderm; g, pronephric glomus; lpm, lateral plate mesoderm; no, notochord; nt, neural tube; so, somites; t, pronephric tubules. Image published in: White JT et al. (2010) Copyright © 2010. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue wt1.S wt-1, wt1-a, wt1-b, Xwt-1, xwt1 X. laevis Throughout NF stage 35 and 36 glomus intermediate mesoderm heart podocyte pronephric kidney foxc2.S fd-4, fkh7, foxc2-a, foxc2-b, MFH-1, Mfh1, XFD-4 X. laevis Throughout NF stage 35 and 36 eye glomus branchial arch hypaxial muscle tail bud mesenchyme pronephric kidney podocyte tcf21.L capsulin, epicardin, pod 1, pod1 X. laevis Throughout NF stage 35 and 36 glomus lateral plate mesoderm branchial arch podocyte pronephric kidney mafb.S kreisler, valentino, xmafb X. laevis Throughout NF stage 35 and 36 lateral plate mesoderm somite glomus early proximal tubule late proximal tubule hindbrain podocyte pronephric kidney eye lens lmx1b.S lmx1.2, lmx1b.1, nps1, Xlmx1b X. laevis Throughout NF stage 35 and 36 eye glomus otic placode ectoderm neural tube podocyte pronephric kidney kirrel1.L kirrel, LOC108699399, LOC108700606, neph1, nephrin-like, nphs1l X. laevis Throughout NF stage 35 and 36 brain eye heart glomus branchial arch tail bud exocrine pancreas nphs1.S nephrin X. laevis Throughout NF stage 35 and 36 glomus podocyte pronephric kidney ptpru.L fmi, glepp1, LOC108708221, LOC108709564, pcp-2, ptp, ptp-j, ptp-pi, ptppsi, ptpro, ptpu2 X. laevis Throughout NF stage 35 and 36 glomus eye brain neural tube podocyte pronephric kidney forebrain nphs2.L nphs2l, podocin X. laevis Throughout NF stage 35 and 36 glomus neural tube podocyte pronephric kidney otic placode Image source: Published Larger Image Printer Friendly View

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