Fig. 6. Confirmation of Xenopus conserved targets. Eight Xenopus targets were confirmed as being regulated by Hoxc6, as shown. In situ hybridizations of control embryos (left in each pair) and of embryos ectopically expressing Hoxc6 (right in each pair). We used probes detecting Xenopus probesets that are also conservedly regulated in Drosophila. These probes detected upregulation (all except Otx2) or downregulation (Otx2). Hoxc6 wild type expression is shown to indicate the normal Hoxc6 expression domain. Shown are stage 12 embryos from the vegetal side (most) or dorsal side (probes MGC82057, LOC495834, and Otx2). The name of each Xenopus target gene is at the top of the right hand picture in each pair.
Image published in: Michaut L et al. (2011)
Copyright © 2011. Image reproduced with permission of the Publisher, John Wiley & Sons.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| hoxc6.S | ACI, xeb1, XlHbox1 | X. laevis | Throughout NF stage 12 | marginal zone ventral marginal zone ventro-lateral marginal zone dorso-lateral marginal zone |
| ccng1.S | MGC53060 | X. laevis | Throughout NF stage 12 | marginal zone |
| rasl11b.L | MGC53580 | X. laevis | Throughout NF stage 12 | marginal zone |
| marchf8.L | LOC495072, march8 | X. laevis | Throughout NF stage 12 | marginal zone ventral marginal zone lower blastopore lip |
| sat1.S | dc21, kfsd, kfsdx, MGC82057, sat1-a, sat1-b, ssat, ssat-1 | X. laevis | Throughout NF stage 12 | dorsal marginal zone |
| herpud1.S | herp, herpud1-a, herpud1-b, mif1, sup | X. laevis | Throughout NF stage 12 | dorsal |
| nfe2.S | LOC495834 | X. laevis | Throughout NF stage 12 | dorsal marginal zone |
| prickle1.S | prickle, prickle1-a, prickle1-b, prickle A, prickle B, Prickle-b, XPk, XPk-1 | X. laevis | Throughout NF stage 12 | marginal zone |
| otx2.S | otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 | X. laevis | Throughout NF stage 12 | dorsal |
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