Figure 2 Developmental expression of Xenopus NLK. (A) RT-PCR analysis shows that xNLK mRNA is maternal and expressed at all stages of early development. Lane numbers correspond to developmental stages: 0, egg; 7, 8, 9, blastula; 10.5, 12, gastrula; 20, neurula; 24, tailbud tadpole; 34, swimming tadpole. (B) Whole-mount in situ hybridization shows the localization of the xNLK transcript. xNLK transcript is distributed to the ectoderm in the early gastrula stages. Views of the vegetal pole ( left) and cross-section (right) are shown and dorsal is right (a). At the neurula ( b) and tailbud tadpole (c) stage, xNLK expression is high in the central nervous system and head. No signal is observed in a stage 32 embryo hybridized with a sense control probe (d). (C) Expression of xSox11 gene in the neural and tailbud tadpole stages. Whole-mount in situ hybridization shows that the xSox11 transcript is high in the central nervous system and head. Lateral views are shown.
Image published in: Hyodo-Miura J et al. (2002)
Copyright © 2002. Image reproduced with permission of the Publisher, John Wiley & Sons.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| nlk.L | nlk1, Xnlk | X. laevis | Throughout NF stage 14 | ectoderm dorsal animal |
| nlk.L | nlk1, Xnlk | X. laevis | Throughout NF stage 20 | neural tube posterior neural tube anterior neural tube |
| sox11.L | sox11-a, sox11-b, XLS13, xls13a, XLS13b, xSOX-11, xsox11 | X. laevis | Throughout NF stage 20 | neural tube posterior neural tube anterior neural tube |
| nlk.L | nlk1, Xnlk | X. laevis | Throughout NF stage 35 and 36 | central nervous system brain spinal cord eye head pharyngeal arch |
| sox11.L | sox11-a, sox11-b, XLS13, xls13a, XLS13b, xSOX-11, xsox11 | X. laevis | Throughout NF stage 35 and 36 | head central nervous system brain spinal cord |
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