Larger Image Fig. 6. Laser confocal immunolocalization of the xrds proteins. (A) Labeling of Xenopus retina with xrds38 peptide antiserum shows rod (r) and cone (c) outer segment immunoreactivity. For all antibodies, rod outer segments (os) showed a striated pattern, reflecting the labeling of disc incisures. Cone outer segments were labeled along one side only. In this region, the stacked cone discs form rds/peripherin-rich hairpin loops that lie in register. (B) Labeling with xrds35 antiserum. Rod (r) but not cone (c) outer segments show immunoreactivity. (C) Labeling with xrds36 antiserum. Rod (r) but not cone (c) outer segments show immunoreactivity. The myoid (m) regions of inner segments and the synaptic terminii (s) of cones are also labeled, but this labeling was not blockable by preincubating the antiserum with the immunizing xrds36 peptide. Bar, 6 mm. Image published in: Kedzierski W et al. (1996) Copyright © 1996. Image reproduced with permission of the Publisher, The Company of Biologists Ltd.
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