Figure 1. Expression patterns of p2ry4 during early development. WISH of p2ry4 from gastrula to tailbud stage. Stages 10.5 and 11 (a and c, dorsal views; b and d, sagittal hemisections). p2ry4 was expressed in the prospective neuroectoderm and the involuting dorsal and ventral mesoderm at gastrula stage. At stage 10.5, p2ry4 was prominently expressed in the head organizer region (b). Stages 13, 17, 19, and 21 (e, f, h, j, anterior views; k, dorsal view; g, sagittal hemisection; i, transverse section). Stage 28 (l, lateral view; m, transverse section; mâ, highâmagnification image of m). The extirpated brain of tadpole (n, lateral side; o, dorsal side). nc, neural crest; pl, placode cell; anp, anterior neural plate; mhb, midbrainâhindbrain boundary; nt, neural tube; not, notochord; som, somite; cg, cement gland; tel, telencephalon; di, diencephalon; mes, mesencephalon; met, metencephalon. Dotted straight line indicates section plane. Black arrowheads indicate blastopore
Image published in: Harata A et al. (2019)
© 2018 The Authors. Creative Commons Attribution license
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 10.5 | dorsal marginal zone upper blastopore lip involuting marginal zone |
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 11 | involuting marginal zone dorsal marginal zone ventral marginal zone upper blastopore lip |
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 13 | anterior placodal area neural crest neural plate neural plate border |
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 17 | anterior neural fold neural plate |
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 19 | presumptive midbrain-hindbrain boundary neural groove neural plate |
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 21 | presumptive midbrain-hindbrain boundary neural plate neural tube |
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 28 | midbrain midbrain-hindbrain boundary eye pharyngeal region neural tube otic vesicle forebrain hindbrain |
| p2ry4.L | XlP2Y | X. laevis | Throughout NF stage 45 | diencephalon midbrain midbrain-hindbrain boundary hindbrain |
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