Larger Image Fig. 2. Expression of WSTF during Xenopus laevis embryonic development. (A) At stage 18 WSTF is expressed in the closing neural tube. Dashed line indicates plane of section in Fig. 3A. (B) At stage 20/21, expression of WSTF is very strong in the optic cup (arrow), in migrating neural crest cells (arrowhead) and the anterior brain. WSTF expression is also detectable in the neural tube, although to a lower extent. (C and D) WSTF expression at stage 24/25 persists strongly in the optic cup (arrow) and the migrating neural crest cells (arrowhead) and weaker in the neural tube. Dashed line indicates plane of section in Fig. 3B. (E) At stage 32, expression of WSTF in the forebrain has ceased whereas expression in the dorsal midbrain (tectum) and the mid/hindbrain-boundary (isthmus) is still bold (arrowhead). Pronounced WSTF expression is also detectable in the branchial arches (white arrowhead). Another tissue exhibiting WSTF expression is the embryonic tailbud. Dashed line indicates plane of section in Fig. 3C. Image published in: Cus R et al. (2006) Copyright © 2006. Image reproduced with permission of the Publisher, Elsevier B. V.
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