Fig. 9. Expression of wild-type Stbm elicits neural tube closure defects and failure of neural convergent extension. (A) Control embryo at mid-neurulation with closing NT. (B) Stbm-injected embryo with defective NT closure. (C) Xfd12 expression in control embryo at stage 14. (D) Xfd12 expression reveals defective neural convergent extension in a stage 14 Stbm-injected embryo. (E) Expression of Xpax3 in a control embryo. (F) Expression of Xpax3 in an XStbm injected embryo. (G) Expression of Xash3 in a control embryo. (H) Expression of Xash3 in an XStbm-injected embryos. (I) Expression of Sox2 in a control embryo. (J) Expression of Sox2 in an XStbm-injected embryos.
Image published in: Wallingford JB and Harland RM (2002)
Copyright © 2002. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| ascl3.L | bhlha42, bhlha44, hash4, LOC108704349, sgn1 | X. laevis | Throughout NF stage 13 to NF stage 21 | neural plate anterior neural tube presumptive midbrain-hindbrain boundary anterior placodal area |
| pax3.S | cdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3 | X. laevis | Throughout NF stage 13 to NF stage 21 | neural plate |
| sox2.L | anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 | X. laevis | Throughout NF stage 13 to NF stage 21 | neural plate |
| foxd4l1.2.L | foxd5.2, foxD5a, FXD12, Xfd-12, Xfd12 | X. laevis | Throughout NF stage 14 |
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