Fig. 3. Whole-mount in situ hybridization showing the localization of Ptc-1 (AâC,S,V,X), Ptc-2 (DâF,T,W,Y), Shh (GâI,U,Z), Gli-1 (JâL), Gli-2 (MâO) and Gli-3 (PâR). (A,D,G,J,M,P) Dorsal views at stages 14. (B,E,H,K,N,Q) Lateral views at stage 26. (C,F,I,L,O,R) Lateral views at stage 31. (SâU) Lateral views of facial regions at stage 31. (V, W) Transverse sections at stage 14. (XâZ) Transverse sections through spinal cord and notochord at stage 27. Embryos in (B,C,E,F,H,I,K,L,N,O,QâU) were cleared by benzyl alcohol-benzyl benzoate.
Image published in: Takabatake T et al. (2000)
Copyright © 2000. Image reproduced with permission of the Publisher, Elsevier B. V.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| ptch1.S | patched, patched1, Ptc-1, Ptc1, X-ptc1, XPtc1 | X. laevis | Throughout NF stage 14 | neural plate |
| shh.L | hedgehog, vhh-1, Xhh, X-SHH, xshh | X. laevis | Throughout NF stage 14 | dorsal neural plate neural groove |
| ptch2.L | patched 2, patched-2, ptc-2, ptc2, ptch2-a, ptch2-b, xptc 2, xptc-2 | X. laevis | Throughout NF stage 14 | presomitic mesoderm |
| gli1.S | Gli-1, X-gli1 | X. laevis | Throughout NF stage 14 | neural plate |
| ptch2.L | patched 2, patched-2, ptc-2, ptc2, ptch2-a, ptch2-b, xptc 2, xptc-2 | X. laevis | Throughout NF stage 26 | somite posterior |
| gli1.S | Gli-1, X-gli1 | X. laevis | Throughout NF stage 26 | somite posterior |
| shh.L | hedgehog, vhh-1, Xhh, X-SHH, xshh | X. laevis | Throughout NF stage 26 | notochord head prechordal plate dorsal |
| ptch1.S | patched, patched1, Ptc-1, Ptc1, X-ptc1, XPtc1 | X. laevis | Sometime during NF stage 26 to NF stage 31 | epidermis somite dorsal neural tube brain midbrain hindbrain olfactory placode optic vesicle otic vesicle branchial arch cranial ganglion pronephric kidney proctodeum tail bud dermatome |
| ptch2.L | patched 2, patched-2, ptc-2, ptc2, ptch2-a, ptch2-b, xptc 2, xptc-2 | X. laevis | Throughout NF stage 31 | notochord |
| gli1.S | Gli-1, X-gli1 | X. laevis | Throughout NF stage 31 | notochord |
| shh.L | hedgehog, vhh-1, Xhh, X-SHH, xshh | X. laevis | Throughout NF stage 31 | notochord head prechordal plate dorsal |
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