Fig. 3. Del1 is essential for the formation of anterior brain tissues. (A) Expression pattern of Del1 at the early neurula stage (sagittal section; anterior side is left). AN, anterior neuroectoderm; PC-AME, prechordal anterior mesendoderm. (B,C) Effects of animal cell injection of 5mis-MO (12.5 ng) or Del1-MO (12.5 ng) at the 8-cell stage. (D-O) Effects on expression of neural markers of animal cell injection of Del1-MO (25 ng) at the 8-cell stage (E,H,K,N). These effects were rescued by co-injecting MO-insensitive Del1 mRNA (100 pg) (F,I,L,O). Compare with controls (D,G,J,M). mix, mixed probes (Six3, En2, Krox20 and HoxB9).
Image published in: Takai A et al. (2010)
Copyright © 2010. Image reproduced with permission of the Publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| edil3.L | DEL-1, XDel1 | X. laevis | Throughout NF stage 13 to NF stage 21 | pre-chordal neural plate anterior neuroectoderm endomesoderm |
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