Fig. 4. Whole-mount in situ hybridization analysis of Xenopus protein tyrosine phosphatase a (XPTPa) mRNA expression in early Xenopus development. A: Vegetal view of mid-gastrula stage embryos hybridized with digoxigenin-labeled sense (left) or anti-sense (right) XPTPa RNA probes. The arrowhead indicates the future dorsal aspect of the embryo. B: Lateral view of a stage 18/19 embryo. The anterior is to the left. C: Lateral view of a stage 22 embryo. Highest levels of XPTPa transcript expression appear in the forebrain (fb) indicated by the arrowhead. D: Dorsal view of a stage 24 embryo. Intense staining is evident in the forebrain (fb) and expression is now also seen in the visceral arches (va). E: Lateral view of a stage 27/28 embryo. F: Lateral view of a stage 31/32 embryo. Prominent staining can be seen in the forebrain (fb), epiphysis (ep), hindbrain (hb), and visceral arches (va). Some staining is also apparent in the otic vesicle.
Image published in: Yang CQ and Friesel R (1998)
Copyright © 1998. Image reproduced with permission of the Publisher, John Wiley & Sons.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| ptpra.S | heptp, hlpr, hptpa, hptpalpha, lrp, ptpa, ptprl2, rptpa, r-ptp-alpha, XPTPa | X. laevis | Throughout NF stage 11 | marginal zone ectoderm |
| ptpra.S | heptp, hlpr, hptpa, hptpalpha, lrp, ptpa, ptprl2, rptpa, r-ptp-alpha, XPTPa | X. laevis | Throughout NF stage 18 to NF stage 19 | anterior posterior |
| ptpra.S | heptp, hlpr, hptpa, hptpalpha, lrp, ptpa, ptprl2, rptpa, r-ptp-alpha, XPTPa | X. laevis | Throughout NF stage 22 | brain forebrain anterior neural tube |
| ptpra.S | heptp, hlpr, hptpa, hptpalpha, lrp, ptpa, ptprl2, rptpa, r-ptp-alpha, XPTPa | X. laevis | Throughout NF stage 24 | brain cranial neural crest forebrain hindbrain |
| ptpra.S | heptp, hlpr, hptpa, hptpalpha, lrp, ptpa, ptprl2, rptpa, r-ptp-alpha, XPTPa | X. laevis | Throughout NF stage 27 to NF stage 32 | pharyngeal arch mandibular arch hyoid arch branchial arch otic vesicle brain forebrain hindbrain pineal gland trunk neural crest |
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