Fig. 5. Distribution of cH2AX in ZZ and ZW gonads during development. Immunostaining with anti-Dmrt1 and anticH2AX antibodies was performed on gonadal sections from ZW and ZZ tadpoles at stages 53 and 62 (A) and on gonadal sections from a ZZ adult frog (B). Nuclei were stained with TO-PRO. Oc, oocyte; POg, primary oogonium; PSg, primary spermatogonium; Sg, secondary spermatogonium; Sc, spermatocyte. White arrowheads and arrows indicate Dmrt1- or cH2AX-positive primary GSCs and leptotene/zygotene oocytes, respectively.
Image published in: Fujitani K et al. (2016)
© 2016 The Authors. Creative Commons Attribution license
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| dmrt1.L | dmrt1-a, dmrt1-b, dmt1, xdmrt1 | X. laevis | Throughout adult frog stage | secondary spermatogonium primary spermatogonium testis |
| h2ax.S | h2afxl, h2a.x, h2a/x, h2axl | X. laevis | Throughout adult frog stage | secondary spermatogonium primary spermatogonium testis spermatocyte |
| dmrt1.L | dmrt1-a, dmrt1-b, dmt1, xdmrt1 | X. laevis | Throughout NF stage 53 | ovary primordial germ cell testis |
| h2ax.S | h2afxl, h2a.x, h2a/x, h2axl | X. laevis | Throughout NF stage 54 to prometamorphosis stage | testis ovary primordial germ cell |
| dmrt1.L | dmrt1-a, dmrt1-b, dmt1, xdmrt1 | X. laevis | Throughout NF stage 62 | secondary oogonium primary oogonium primary spermatogonium ovary |
| h2ax.S | h2afxl, h2a.x, h2a/x, h2axl | X. laevis | Throughout NF stage 62 | oocyte testis ovary |
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